research Phytochemicals With Anti 5-alpha-reductase Activity: A Prospective For Prostate Cancer Treatment
Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.
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research Letter to the Editor on “COVID-19 Infection in Men on Testosterone Replacement Therapy”
The letter suggests testosterone replacement therapy might worsen COVID-19 outcomes.
research Formononetin: Novel Deal for Androgenetic Alopecia
Formononetin, found in red clover, may treat hair loss with fewer side effects.
research Serum androgens and prostate-specific antigen levels in androgenetic alopecia: is there a difference between frontal and vertex baldness?
Vertex baldness has higher DHT levels than frontal baldness, but testosterone and PSA levels are similar.
research Effect of Carbamates on mRNA Encoding Lipid Enzymes in Hamster Flank Organs
Carbamates may help treat androgen-dependent conditions by changing how certain lipid enzymes are produced.
research Evaluating the safety profile of α-1 blockers, 5α-reductase inhibitors, and PDE5I for BPH: a disproportionality analysis of real-world adverse events based on FDA adverse event reporting system (FAERS)
PDE5 inhibitors cause earlier adverse events in BPH treatment, requiring careful monitoring.
research Pharmacologically altered Androgens, Brain Activation and Response Inhibition in a Stop-Signal Task in Male Heavy Drinkers
Lower DHT and higher testosterone levels increase brain activation but don't change behavior in heavy drinkers.
research An exploratory analysis of 5‐alpha reductase inhibitors and risk of opioid use disorder among male Medicare beneficiaries receiving prescription opioid medications
Using 5-alpha reductase inhibitors may lower the risk of opioid addiction in men taking opioids.
research Geographic Influence and Metabolomics-Driven Discovery of 5-Alpha Reductase Inhibitors in Tectona grandis L.f. (Teak) Leaves
Teak leaf extract can help treat hair loss, and its effectiveness varies by geographic origin.
research Suicidality Risks Associated with Finasteride, a 5-Alpha Reductase Inhibitor: An Evaluation of Real-World Data from the FDA Adverse Event Reports
Finasteride use may increase suicidality risk, especially in young men.
research Preparation, Characterization and Molecular Docking Study of some New Pyrazole Derivatives Derived from 2-Mercaptobenzothiazole.
New pyrazole derivatives may help treat hair loss, but more testing is needed.
research Effects of Nano-cerium Oxide on the Levels of DHT, TGF-β, and IGF-1 in the Local Skin of AGA Model Mice and Efficacy Observation
Nano-cerium oxide may help treat hair loss by improving hair growth and reducing certain skin proteins.
research Inhibition of 5-Alpha Reductase Attenuates Cardiac Oxidative Damage in Obese and Aging Male Rats via the Enhancement of Antioxidants and the p53 Protein Suppression
Finasteride improves heart function in obese and aging male rats by reducing oxidative stress and p53 protein levels.
research Fructus Psoraleae Treating in Androgenetic Alopecia Through 5-Α Reductase Inhibition and Nrf2-Keap1 Pathway
Fructus Psoraleae may help treat hair loss by inhibiting 5-α reductase and affecting the Nrf2-Keap1 pathway.
research 5 Alpha-Reductase Inhibitory Potential of Solanum nigrum Effective for Management of Alopecia
Solanum nigrum may help treat hair loss.
research Androgenic Alopecia and Homoeopathic Management
Homeopathy can effectively treat pattern hair loss by using remedies like Lycopodium Clavatum and Natrum Muriaticum, tailored to the patient's overall condition.
research Synthesis of novel andostane-N-cyclohexyl-17-carboxamides, and their effect on the 5α-reductase isoform 2, the androgen receptor, and androgen-dependent glands
New compounds were made and tested, with compound 6 showing potential for treating prostate-related diseases.
research Aknede Hormonal Tedavi
Hormonal treatments effectively manage acne in some women, especially with specific hormonal issues.
research Endocrinology Overview RSS
The document explains how male reproductive hormones work and affect the body.
research Finasteride as a positive control on reproduction studies
Finasteride causes reproductive malformations in male rats.
research Hair Transplantation
Hair transplantation is a treatment for hair loss mainly caused by genetics, with various techniques and potential complications, and results visible after 8-12 months.
research Post-Finasteride Syndrome: An Underestimated Phenomenon
Finasteride and dutasteride, used for prostate issues and hair loss, can cause side effects like sexual dysfunction and mental issues, which may continue even after stopping the medication, a condition called post-finasteride syndrome, for which there's currently no cure.
research Clinical trial and in vitro study investigating topical application of Zataria multiflora Boiss. and Matricaria chamomilla extracts for androgenetic alopecia
Extracts improve hair growth in alopecia.
research Androgenetic alopecia, hirsutism and hypertrichosis
Hair loss and excessive growth treated with various options, including new laser technology.
research Dihydrotestosterone-Inducible Dickkopf 1 from Balding Dermal Papilla Cells Causes Apoptosis in Follicular Keratinocytes
A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.
research Finasteride
Finasteride effectively treats baldness but may cause sexual side effects.
research Androgens and androgen receptor action in skin and hair follicles
Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.
research Androgenetic alopecia: An update
Minoxidil and finasteride effectively treat hair loss.
research Acne
Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.
research Finasteride Inhibits Human Prostate Cancer Cell Invasion through MMP2 and MMP9 Downregulation
Finasteride may reduce prostate cancer spread by lowering certain enzyme levels.