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Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

Stress increases neurosteroids that help prevent seizures.

Women with hair loss had higher levels of certain hormones, suggesting a link to a condition like PCOS.

Dutasteride is more effective than finasteride for hair loss treatment.

Finasteride harms Daphnia magna's reproduction, growth, and metabolism.

Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.

Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.

Rodent models of PCOS show some hormone changes similar to humans, but also have key differences.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Testosterone's muscle-building effects do not require its conversion to DHT.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Some dibenzo compounds might help treat cancer with fewer side effects.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Low dose finasteride decreases certain steroids, possibly increasing depression risk.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Finasteride effectively treats male hair loss, improving growth and density.

Cinnamomi cortex may help treat prostate enlargement by reducing related proteins.

High doses of finasteride cause cell growth and tumors in mice.

Certain Dibenzo derivatives may help treat prostate cancer.

Finasteride causes abnormal growth in male mice cells at high doses.