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Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.

Females with 5 alpha-reductase-2 deficiency have less body hair, no acne, normal fertility, and delayed menarche.

Different mutations in the 5 alpha-reductase-2 gene were found in affected individuals in the Dominican Republic, suggesting no common ancestry.

Spironolactone reduces the enzyme activity that converts testosterone to DHT, helping treat excessive hair growth in women.

A new drug, dutasteride, is at least as effective as the older drug, finasteride, for treating enlarged prostate and may have additional uses.

Four new compounds were more effective than finasteride in treating prostate issues and hair loss, with one being 100 times more active and safe for use.

5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.

Some men's prostate tissues have low enzyme levels due to genetic changes, possibly affecting treatment for prostate enlargement.

5-alpha-reductase inhibitors may reduce COVID-19 symptoms in bald males.

Finasteride and minoxidil together promote hair growth better than either alone.

Finasteride reduces hair growth and is safe for women with excessive hair.

5-alpha reductase inhibitors are generally safe but can cause sexual side effects and require patient education on risks.

Using finasteride or dutasteride does not increase the risk of male breast cancer.

Finasteride doesn't affect hormone levels in normal men.

Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.

Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

5-alpha-reductase inhibitors may help stabilize or slow down hair loss in some frontal fibrosing alopecia patients, but more research is needed to confirm their effectiveness and safety.

Men taking 5-alpha-reductase inhibitors before or after bladder cancer diagnosis had a lower risk of dying from the disease.

New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.

Using 5 alpha reductase inhibitors may increase dementia risk in the first two years.

No link found between specific genes and female pattern hair loss.

Compounds from the plant Mammea siamensis may help treat hair loss.

Finasteride helps with prostate symptoms but may cause sexual side effects.

Dutasteride is the most effective hair loss treatment after 24 weeks, but finasteride leads to the most hair growth after 48 weeks.

Certain drugs change freshwater snail shells to a "banana" shape.

LH and hCG reduce certain protein levels in women's skin.

Men on 5-alpha-reductase inhibitors might have worse COVID-19 outcomes.

The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.

Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.