55 citations
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June 2012 in “Steroids” Testosterone affects vascular cells directly without converting to estradiol.
13 citations
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September 2013 in “Steroids” The DHT immunoassay is unreliable due to high cross-reactivity with testosterone.
22 citations
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January 2017 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” A new method accurately measures nine specific hormones in human blood.
59 citations
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September 2003 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Epitestosterone may counteract testosterone's effects and has roles in body processes like prostate growth and hair distribution.
AGA causes permanent hair loss; women use 2% minoxidil, men use 1 mg finasteride daily.
27 citations
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April 1996 in “Baillière's clinical endocrinology and metabolism” The document says that understanding the causes of PCOS is important for treatment, especially in distinguishing the syndrome from just having cystic ovaries, and that losing weight is key for obese women with PCOS.
February 2020 in “Benha Journal of Applied Sciences” Insulin resistance and nesfatin-1 are linked to acne severity.
9 citations
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January 1997 in “Gynecological Endocrinology” The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.
1 citations
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March 2021 in “Skin health and disease” Better hair loss models needed for research.
43 citations
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January 2016 in “International Journal of Andrology” Finasteride caused long-term sexual and non-sexual side effects in young men with hair loss.
42 citations
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June 2020 in “Seminars in Oncology” Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.
October 2020 in “System Dynamics Review” The document concludes that finasteride can reduce nandrolone detection in doping tests, suggesting frequent testing and setting metabolite level thresholds for detection.
20 citations
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October 2018 in “Clinical Drug Investigation” Dutasteride does not impair mental function in elderly men with enlarged prostate.
16 citations
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September 2014 in “International Journal of Biological Markers” Longer CAG and GGN repeats increase alopecia risk, but no significant link to post-finasteride syndrome found.
139 citations
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December 2020 in “Cell Stem Cell” Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
7 citations
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April 2015 in “JAMA Dermatology” Finasteride's potential harms are hard to accurately measure.
233 citations
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November 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.
122 citations
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November 2010 in “Journal of Dermatological Science” Male pattern baldness involves hormones and cell signals affecting hair growth.
77 citations
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May 2012 in “Expert Opinion on Emerging Drugs” New treatments for male hypogonadism are effective and should be personalized.
2 citations
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January 2011 in “Clinical medicine insights” Dutasteride is effective for treating prostate enlargement and reducing related surgery risk, but is not approved for preventing prostate cancer.
21 citations
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June 2005 in “Alcoholism: Clinical and Experimental Research” Finasteride reduces alcohol withdrawal severity and anxiety in mice, but may increase withdrawal severity in some cases.
14 citations
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October 2020 in “Natural Products and Bioprospecting” Various treatments, including FDA-approved drugs, natural products, and oral supplements, can help with hair loss, but a patient's medical history and potential allergies should be considered when choosing a treatment.
260 citations
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July 2010 in “Cell” Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.
81 citations
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June 2010 in “Journal of Dermatological Treatment” The document concludes that minoxidil and finasteride are proven for hair growth, herbal remedies show promise, but more research is needed to confirm their effectiveness.
14 citations
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January 2019 in “Skin appendage disorders” PFS might be a delusional disorder with potential to become mass psychogenic illness.
November 2020 in “Elsevier eBooks” Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.
20 citations
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November 2019 in “Biomolecules” Finasteride reduces response to stress and rewards, affecting behavior and mental health.
33 citations
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October 2004 in “Archives of Dermatological Research” Large prostate links to more hair loss, but age of onset doesn't affect it.
24 citations
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December 2013 in “Sexual medicine reviews” Finasteride can cause sexual problems and depression in young men.
18 citations
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May 2015 in “Australasian Journal of Dermatology” Serenoa repens extract in topical products improves hair growth and appearance in male pattern baldness with mild side-effects.