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Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Two new compounds were found to effectively reduce hair growth in mice.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

3-tetrazolo steroidal analogs can strongly inhibit the enzyme linked to hair loss.

5-Alpha-Reductase Inhibitors can cause negative side effects.

5α-Reductase inhibitors don't cause depression.

Medicines called 5-alpha-reductase inhibitors, like finasteride and dutasteride, are useful for treating enlarged prostate and male pattern hair loss.

The document's conclusion cannot be provided because the document is not available or cannot be read.

Prescriptions for 5-alpha reductase inhibitors dropped significantly after the FDA's safety warning, especially for men with benign prostatic hyperplasia.

5α-reductase inhibitors can reduce prostate cancer risk but may increase high-grade tumors, needing more research.

Finasteride may help improve certain brain function issues linked to dopamine.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

Higher levels of miR-1199-5p may reduce the effectiveness of certain prostate treatments.

The equine epididymis mainly uses type 1 5α-reductase, and both finasteride and dutasteride can inhibit its activity.

Combining dutasteride or finasteride with an α1 blocker is more effective for managing BPH than using either alone.

A new drug, dutasteride, is at least as effective as the older drug, finasteride, for treating enlarged prostate and may have additional uses.

The compounds tested could potentially treat hair loss and alopecia.

11β-Hydroxylase inhibitors help prevent seizures in mice by boosting natural neurosteroid production.

Starting 5-alpha reductase inhibitors does not significantly increase the risk of rhabdomyolysis in older men, but is linked to a higher risk of muscle conditions.

A reliable model for screening type II 5α-reductase inhibitors was created and validated.

5-alpha-reductase inhibitors might help slow down low-risk prostate cancer, but their use should be cautious.

Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.

Epristeride's metabolism involves key metabolites and proteins, affecting its use in doping tests.

A stronger dual 5α-reductase inhibitor could improve treatment for benign prostatic hyperplasia by further reducing DHT levels.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

A new compound from a sponge strongly inhibits an enzyme linked to male-pattern hair loss without being toxic at low levels.

Inhibiting PLA2 enzymes may help treat inflammatory skin diseases like psoriasis and dermatitis.