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Inhibiting 5α-reductase during late pregnancy shortens gestation, reduces litter size, and harms memory in rat offspring.

Teak leaf extract contains compounds that could help treat hair loss.

Certain drugs can block changes in brain receptors caused by alcohol withdrawal.

2-DG reduces seizures by enhancing brain inhibition through specific receptor activation.

Taking medication for hair loss might cause sexual problems.

Cepharanthine analogues, especially tetrandrine, show potential for treating COVID-19.

Finasteride blocks progesterone's effect on absence seizures in rats.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

Mimosine dipeptides are promising for treating hyperpigmentation and inflammation.

Anti-androgen drugs can help reduce OCD symptoms, but more large-scale trials are needed to confirm their effectiveness.

Women also use 5α-reductase inhibitors for hair loss and hirsutism.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

Some synthetic carbohydrate receptors, especially compounds 3 and 15, show strong potential for treating Zika virus.

Using 5-α-reductase inhibitors before treatment improves outcomes for patients with metastatic renal cell carcinoma.

Finasteride reduces prostate cancer risk but may increase high-grade tumors; new drugs and better diagnosis are in development, but funding and industry commitment are challenges.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Finasteride reduces heart enlargement and improves heart function.

PADI4 enzyme slows down cell growth in developing hair follicles.

Monocyclic aromatic compounds are important for developing various drugs and treatments.

Neurosteroids may help treat disorders with too much dopamine activity.

Isotretinoin shows promise as a treatment for Chagas disease by effectively inhibiting key transporters in the parasite.

Etifoxine, an anxiety drug, can lessen brain inflammation and cognitive issues in mice, partly by increasing production of protective brain steroids.

Drug approvals slowed in 2Q22, but notable drugs like Amvuttra, Camzyos, and Olumiant were approved.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

Early sunburn treatment with certain inhibitors may reduce skin cancer risk.

The conclusion is that doctors should be careful when prescribing 5α-reductase inhibitors due to possible serious side effects, and they should discuss these risks with patients.

Cepharanthine and Trifluoperazine are effective against SARS-CoV-2.

Muscles can make their own androgens, which may help muscle growth.

5-alpha reductase inhibitors do not increase hip fracture risk.