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The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

Thai plant extracts, especially Avicennia marina, can promote hair growth by inhibiting certain enzymes and boosting growth factors.

Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

A compound from brown algae boosts the production of a certain inflammatory substance in skin cells.

5α-reductase inhibitors can reduce prostate cancer risk but may increase high-grade tumors, needing more research.

The market for these drugs is expected to grow.

Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.

5-Alpha reductase inhibitors help treat enlarged prostate but may cause sexual side effects.

ALKBH5 helps wounds heal faster by stabilizing PELI2 mRNA.

Inhibiting certain enzymes made female rats more sensitive to low-level pain.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

New model shows muscle affects hair loss differently in men and women.

Dutasteride effectively and safely treats male hair loss for over a year.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

A reliable model for screening type II 5α-reductase inhibitors was created and validated.

MOF controls key genes for skin development by regulating mitochondrial and ciliary functions.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

5α-Reductase inhibitors can negatively impact sexual function.

Androgens like testosterone increase colon muscle contractions by affecting calcium pathways.

MOF controls skin development by regulating genes for mitochondria and cilia.

Carthamus oxyacantha may help treat BPH by inhibiting 5α-reductase.

Blocking certain brain processes reduces mating behavior in female rats.

The saw palmetto extract effectively inhibits an enzyme linked to prostate issues, showing promise for prostate health.

Atg5 can promote tumors when autophagy is deficient but suppresses them under normal conditions.

Oleanolic acid improved hair growth in mice by affecting hair growth pathways and reducing inflammation.

Human skin can make serotonin and melatonin.