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Researchers developed a new way to measure gene activity in single hair follicles and found that a specific gene's activity changes with different amounts and times of treatment.

TPA strongly increases ODC activity in certain skin cells, potentially aiding tumor growth.

Adding a specific gene to skin cells can help treat skin disorders like psoriasis.

The P133R mutation in AKR1D1 enzyme causes harmful bile acid buildup, explaining related health issues.

Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.

Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.

Avicequinone C, a compound found in the Avicennia marina plant, can reduce hair loss by inhibiting a hormone linked to androgenic alopecia.

New compounds were made that effectively block enzymes related to prostate issues and hair loss.

Lack of 5α-Reductase type 1 can lead to insulin resistance and liver problems.

4-O-Methylhonokiol helps protect skin cells from growth-stopping effects of a protein by regulating growth-related pathways.

New pyrazole-based inhibitors show promise for treating metabolic diseases and other conditions.

Inhibiting certain enzymes made female rats more sensitive to low-level pain.

New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.

Blocking CYP17A1 enzyme may help improve certain brain function issues related to dopamine.

Androgens increase muscle mass by promoting myoblast growth through ornithine decarboxylase.

Androgen receptors help prostate cancer cells grow and resist drugs.

Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.

Editing the FGF5 gene in sheep increases wool length, confirming its role in hair growth.

Androgens regulate 5 alpha-reductase activity in hamster sebaceous glands.

Certain alkaloids could help create new coronavirus drugs.

Ocimum basilicum L. and red Oryza sativa L. may help with hair loss and prostate issues.

Different mutations in the 5 alpha-reductase-2 gene were found in affected individuals in the Dominican Republic, suggesting no common ancestry.

Analog 23 is a promising compound for prostate cancer treatment.

Finasteride's molecular properties and active sites were identified using computational methods.

Blocking a key energy pathway in human hair follicles can trigger stress responses that stop cell growth.

Blocking a certain signal in the gp130 receptor can improve tissue healing and lessen osteoarthritis symptoms.

The development of breeding tubercles in male zebrafish relies on a specific enzyme that processes hormones.

A new method was developed to accurately measure enzyme activity related to prostate health.