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research Two-ligand priming mechanism for potentiated phosphoinositide synthesis is an evolutionarily conserved feature of Sec14-like phosphatidylinositol and phosphatidylcholine exchange proteins

25 citations , May 2016 in “Molecular biology of the cell”

A protein in plants needs to bind two lipids to help with root hair growth, and this process is similar across different plant species.

research 5ARIs and PSA: Evidences

3 citations , May 2014 in “Urologia Journal”

5ARIs lower PSA levels, but other tests are needed to avoid missing aggressive prostate cancer.

research A rapid method for obtaining finasteride, a 5α-reductase inhibitor, from commercial tablets

14 citations , April 2002 in “Brain Research Protocols”

Quickly get finasteride from tablets using easy methods.

DNA Dioxygenases Tet2/3 Regulate Gene Promoter Accessibility and Chromatin Topology in Lineage-Specific Loci to Control Keratinocyte Differentiation and Hair Growth

research 1440 DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control keratinocyte differentiation and hair growth

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

Tet2 and Tet3 enzymes are important for controlling hair growth and shape by affecting gene activity and DNA structure in hair follicles.

research Breaking the ‘rule-of-five’ to access bridged bicyclic heteroaromatic bioisosteres

February 2026 in “Nature Synthesis”

A new method creates unique chemical structures that could improve drug discovery.

research Ultrastructural localization of hair keratins, high sulfur keratin-associated proteins and sulfhydryl oxidase in the human hair

9 citations , February 2016 in “Anatomical Science International”

Hair proteins change location and structure as hair cells mature.

research Charting the Bromodomain BRD4: Towards the Identification of Novel Inhibitors with Molecular Similarity and Receptor Mapping

10 citations , November 2017 in “Letters in drug design & discovery”

Researchers identified promising inhibitors for the BRD4 protein, including finasteride and amentoflavone.

Diphlorethohydroxycarmalol, Isolated from Ishige Okamurae, Increases Prostaglandin E2 through the Expression of Cyclooxygenase-1 and -2 in HaCaT Human Keratinocytes

research Diphlorethohydroxycarmalol, Isolated from Ishige okamurae, Increases Prostaglandin E₂through the Expression of Cyclooxygenase-1 and -2 in HaCaT Human Keratinocytes

9 citations , November 2012 in “Biomolecules & therapeutics”

A compound from brown algae boosts the production of a certain inflammatory substance in skin cells.

Crystallization and Preliminary X-Ray Analysis of the Human Androgen Receptor Ligand-Binding Domain with a Coactivator-Like Peptide and Selective Androgen Receptor Modulators

research Crystallization and preliminary X-ray analysis of the human androgen receptor ligand-binding domain with a coactivator-like peptide and selective androgen receptor modulators

1 citations , November 2008 in “Acta crystallographica”

Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

research Allopregnanolone promotes proliferation and differential gene expression in human glioblastoma cells

25 citations , January 2017 in “Steroids”

Allopregnanolone increases growth and changes gene activity in human brain cancer cells.

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