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LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.

Mutants of CYP154C2 enzyme significantly improved steroid conversion efficiency.

c-Maf positive macrophages help form hypertrophic scars by affecting fibroblasts and collagen production.

Tgm2 helps stabilize dying cells and aids fibroblast attachment to the extracellular matrix.

The A allele of the C2 gene increases the risk of lupus, while the G allele may protect against it.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

A 2-year-old girl with a rare vitamin D disorder had rickets and hair loss, but treatment was ineffective due to poor compliance.

Researchers found a way to make rat hair follicle cells start turning into motor neuron-like cells, but couldn't fully turn them into working motor neurons.

Methylated gene parts may cause finasteride-resistance in some enlarged prostate patients.

ARL15 is important for fat cell development and the release of the hormone adiponectin.

Cyclooxygenase-2 overexpression in mice skin causes hair loss like human androgenetic alopecia.

CARASIL can cause different symptoms even with the same genetic mutation.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

ALKBH5 helps wounds heal faster by stabilizing PELI2 mRNA.

GLI2 activates GLI1, promoting skin tumor growth and hair development.

The same genetic mutation in Sjögren-Larsson syndrome can lead to different levels of severity, suggesting other factors influence the symptoms.

Male cells need DHT to respond to testosterone, while female cells do not.

A gene variation is linked to hair thickness in Asians.

Environmental factors affect reproductive traits by altering the SRD5A1 gene.

A KRT32 gene variant causes loose anagen hair syndrome.

PRDX5 enzyme may contribute to alopecia areata by affecting oxidative stress and autoimmunity.

Two specific hair keratin genes are active during hair growth and decline as hair transitions to rest.

A rare genetic disease causes rickets and often hair loss in young children, which can improve with specific treatments.

Keratin 19 forms less stable and shorter filaments than keratin 14, giving unique traits to certain skin cells.

DPP4-positive fibroblasts play a major role in producing proteins that lead to skin fibrosis.

A specific gene mutation is linked to a hereditary form of dystonia that responds well to certain medications.