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Glucocorticoids reduce fat production in liver cells, while androgens increase it in females; manipulating certain enzymes can influence these effects.

Different forms of FGF5 either promote or inhibit hair growth.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

The K5 promoter controls gene expression in skin cells, with specific DNA segments crucial for targeting and regulation.

The human K5 promoter controls specific gene expression in skin cells, with key regulatory elements near the TATA box.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

MK-0773 is a moderate inhibitor of the SRD5A2 enzyme.

LGR5 mainly stays inside cells, moving to the trans-Golgi network, and this process is important for its role in cell signaling.

TRPM5 is crucial for maintaining hair growth.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

SRD5A2 enzyme expression varies in benign prostates and can be influenced by inflammation, affecting treatment options.

Finasteride effectively inhibits the enzyme steroid 5 alpha-reductase II.

Researchers identified a new variant of the FGF5 gene in sheep that affects hair length.

Different enzymes are active in different parts of developing mouse organs.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

PADI4 enzyme slows down cell growth in developing hair follicles.

A Saudi individual initially identified as a girl had a genetic disorder affecting gender development.

Higher SRD5A2 expression predicts better response to finasteride in treating urinary symptoms.

RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

A new method was developed to measure and assess the activity and inhibition of the enzyme steroid 5α-reductase.

Methylated gene parts may cause finasteride-resistance in some enlarged prostate patients.

5ARI treatment improves PSA test accuracy for prostate cancer diagnosis.

Lack of 5α-Reductase type 1 can lead to insulin resistance and liver problems.

miR-133a-3p and miR-145-5p help goat hair follicle stem cells differentiate by controlling NANOG and SOX9.

Longer TA repeats in the SRD5A2 gene may increase acne risk in Chinese people.

FGF5 spliceosomes inhibit rabbit hair growth by affecting gene expression.