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Neurosteroids and benzodiazepines reduce neuron excitability, with lasting effects on inhibitory neurons.

Finasteride reduces prostate cancer risk but may increase high-grade tumors; new drugs and better diagnosis are in development, but funding and industry commitment are challenges.

CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.

SIG-1451 could be a promising new treatment for atopic dermatitis.

The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.

PMC shows promise as a treatment for hair loss.

A compound from brown algae boosts the production of a certain inflammatory substance in skin cells.

Vepdegestrant may become the first FDA-approved PROTAC degrader, marking a new era in drug development.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Drugs that block GSK-3 show promise for treating various diseases.

Escitalopram might effectively treat delusions of parasitosis and possibly Morgellons disease, with psychological factors being important to consider.

Apremilast may help treat hair loss in alopecia areata.

Tofacitinib can cause unusual hair growth, requiring careful monitoring and possible laser hair removal.

Blocking the enzyme that turns testosterone into DHT can safely and effectively treat enlarged prostate.

Both drugs lower DHT levels, with GI198745 being more effective.

Liarozole may be more effective than cyproterone acetate for treating advanced prostate cancer, with better PSA response and survival rates, while maintaining quality of life.

Mimosine dipeptides are promising for treating hyperpigmentation and inflammation.

5alpha-reductase inhibitors like finasteride and dutasteride effectively treat BPH by reducing DHT, offering symptom relief and potential future uses.

Forsythoside A may help treat hair loss by blocking specific channels.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Thai plant extracts, especially Avicennia marina, can promote hair growth by inhibiting certain enzymes and boosting growth factors.

Certain alkaloids could help create new coronavirus drugs.

Cinnamomi cortex may help treat prostate enlargement by reducing related proteins.

5-Alpha-Reductase inhibitors shorten COVID-19 recovery time in men.

Finasteride may increase depression by reducing brain cell growth.

Ro 10-9359 is an effective treatment for severe psoriasis but can cause side effects.

A reliable model for screening type II 5α-reductase inhibitors was created and validated.