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Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.

Compound 15a was effective in inhibiting 5α-reductase.

New steroids were patented as effective for treating acne, hair loss, and other conditions related to hormones.

Finasteride helps protect brain in old male rats.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.

Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Men taking 5-alpha-reductase inhibitors before or after bladder cancer diagnosis had a lower risk of dying from the disease.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Finasteride negatively affects fish reproduction and gonadal development.

Finasteride improves hair growth in men with androgenetic alopecia.

Testosterone's muscle-building effects do not require its conversion to DHT.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Certain drugs change freshwater snail shells to a "banana" shape.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.

Starting 5-alpha reductase inhibitors does not significantly increase the risk of rhabdomyolysis in older men, but is linked to a higher risk of muscle conditions.

Certain drugs that block specific enzymes can help treat prostate diseases.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.