research Actions of 5α-reductase inhibitors on the epididymis
5α-reductase inhibitors may reduce male fertility and could be used for male contraception.
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660-690 / 1000+ resultsresearch UP-03.20
Combination therapy with Finasteride is more effective than alpha-blocker alone for BPH symptoms in small prostate volume.
research 51794 Compounded Solution to Personalize Alopecia Management
The compounded topical solution is safe, stable, and effective for personalized alopecia treatment.
research The Dark Side of 5α-Reductase Inhibitors' Therapy: Sexual Dysfunction, High Gleason Grade Prostate Cancer and Depression
5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.
research Abstracts
Finasteride significantly increases scalp hair and prevents hair loss in young and middle-aged men.
research Therapeutic Evaluation of Spironolactone and Finasteride in the Treatment of Acne Vulgaris
research Comments concerning the real risk of sexual adverse events secondary to the use of 5-ARIs
The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.
research A multi-centre, double-blind, randomised, vehicle-controlled study for a quantitative estimation of hair re-growth in male subjects with androgenetic alopecia treated over 6 month with two ethanolic PSK 3841 solutions (2.5% and 5%)
research Finasteride as a Neo-Adjuvant Treatment for TURPLiterature Review
Finasteride, a drug that prevents testosterone conversion, can effectively reduce blood loss in prostate surgery, especially for patients with a prostatic volume over 30 cc, and decrease post-surgery complications.
research Nonsteroidal inhibitors of human type I steroid 5-.alpha.-reductase
New compounds called benzoquinolinones may treat conditions linked to excess DHT.
research Finasteride blocks progesterone synthesis in MA-10 Leydig tumor cells
research Evaluation of men on finasteride.
Finasteride reduces prostate size and serum levels, helping manage benign prostatic hyperplasia, without affecting prostate cancer detection. Regular monitoring is needed for users.
research Side Effects Related to 5 α-Reductase Inhibitor Treatment of Hair Loss in Women: A Review.
The review found that women using hair loss drugs like finasteride and dutasteride rarely reported sexual side effects.
research The Effects of Oral 5-alpha Reductase Inhibitors on Penile Intracavernosal Pressures and Penile Morphology in Rat Model.
Oral finasteride and dutasteride may negatively affect erectile function in rats.
research [Effect of selective 5alpha-reductase inhibitor or/and testosterone undecanoate on the reproductive function of male rats].
Testosterone undecanoate can reduce the negative effects of Finasteride on male reproductive health.
research Δ5-3β-Hydroxysteroid Dehydrogenase Activity in Sebaceous Glands of Scalp in Male-Pattern Baldness
research Efficacy and safety of topical GT20029 in male patients with androgenetic alopecia: a multicenter, randomized, double-blind, placebo-controlled phase 2 study
Topical GT20029 effectively promotes hair regrowth and is well-tolerated.
research Post-Finasteride Syndrome: An Underestimated Phenomenon
Finasteride and dutasteride, used for prostate issues and hair loss, can cause side effects like sexual dysfunction and mental issues, which may continue even after stopping the medication, a condition called post-finasteride syndrome, for which there's currently no cure.
research Invalidation of a commercially available human 5α-dihydrotestosterone immunoassay
The DHT immunoassay is unreliable due to high cross-reactivity with testosterone.
research Comparative study between topical minoxidil 5% and oral spironolactone versus topical minoxidil 5% and oral dutasteride in the treatment of women with androgenic alopecia
research Finasteride-related sexual and neuropsychiatric AEs
research Figure 10, Photographic evaluation of treatment response to finasteride a – pre treatment b – post treatment
research Value of hormonal levels in patients with male androgenetic alopecia treated with finasteride: better response in patients under 26 years old
Finasteride works better for hair loss in patients 26 or younger.
research A Comparison of Varying alpha-Blockers and Other Pharmacotherapy Options for Lower Urinary Tract Symptoms.
Alpha-blockers are the most effective and widely used treatment for lower urinary tract symptoms, with minimal side effects.
research Evidence for the efficacy and safety of tadalafil and finasteride in combination for the treatment of lower urinary tract symptoms and erectile dysfunction in men with benign prostatic hyperplasia
Taking tadalafil and finasteride together is safe and effective for treating urinary symptoms and erectile dysfunction in men with enlarged prostates.
research Three isostructural solvates of finasteride and their solid-state characterization
Three new finasteride solvates found, change forms under different drying conditions.
research Prostaglandins in androgenetic alopecia in 12 men and four female
research Post-Finasteride Adverse Effects in Male Androgenic Alopecia: A Case Report of Vitiligo
Finasteride may cause vitiligo, sexual issues, and depression; better treatments and predicting side effects needed.
research Hidradenitis suppurativa in pediatric patients treated with finasteride: A case series
Finasteride improved hidradenitis suppurativa in kids without side effects.