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January 2009 in “The Chinese Journal of Dermatovenereology” Higher doses of Tribulus terrestris extract increase MC-1R expression in mouse hair follicles.
April 2008 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” The vitamin D receptor helps control hair growth and may protect against certain skin tumors.
The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.
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Newer retinoid drugs are effective for skin conditions but have significant side effects.
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August 2019 in “Journal of the American Academy of Dermatology” Frontal fibrosing alopecia may be caused by an autoimmune reaction and hormonal imbalance.
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RXR and RAR proteins in skin may help with cell growth, hair growth, and gland function.
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February 2007 in “The EMBO Journal” Fgfr2b helps maintain healthy skin and prevent cancer.
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October 2016 in “Stem Cells and Development” Epidermal growth factor helps hair stem cells grow by activating specific cell pathways.
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July 2012 in “Translational Psychiatry” Memantine may slightly improve memory in people with Down syndrome, but more research is needed.
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January 2014 in “Dermatology research and practice” Skin side effects from cancer drugs targeting EGFR can affect treatment adherence but can be managed with antibiotics like tetracycline.
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May 2015 in “Archives of dermatological research” PPAR agonists show promise for skin conditions but need more research before being a main treatment.
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March 2020 in “Scientific Reports” EGFR-TKIs can cause significant skin, nail, and organ side effects.
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February 2013 in “Journal of Biological Chemistry” LGR5 mainly stays inside cells, moving to the trans-Golgi network, and this process is important for its role in cell signaling.