83 citations
,
May 2011 in “Experimental Dermatology” Sheep have 17 keratin genes, similar to humans, but with different expression patterns affecting wool and hair.
63 citations
,
July 2006 in “British Journal of Dermatology” Psoriasis causes changes in certain keratins and shrinks sebaceous glands in the scalp.
40 citations
,
April 1999 in “Journal of Histochemistry & Cytochemistry” S100A3 protein is mainly found in specific parts of human hair cells.
April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” CTCF protein is essential for skin and hair follicle development in mice.
54 citations
,
January 1995 in “Human Molecular Genetics” Monilethrix is linked to a gene cluster on chromosome 12.
22 citations
,
July 1998 in “Journal of Investigative Dermatology” The 4C32 gene may help in mouse skin development and differentiation.
September 1997 in “Clinical and Experimental Dermatology” 32 citations
,
October 1985 in “Annals of the New York Academy of Sciences” Keratin genes help explain how hair and feathers develop differently in mammals and birds.
15 citations
,
January 1996 in “Adelaide Research & Scholarship (AR&S) (University of Adelaide)” Keratin gene regulation was emerging, with a key transcription factor found to influence hair growth and gene expression.
30 citations
,
January 1994 in “Micron” Mature hair surfaces are formed by keratinized cells with developed layers, not just modified plasma membranes.
9 citations
,
January 1981 Nucleophilic reagents break down hair keratin, forming more lanthionine and lysinoalanine than in wool.
15 citations
,
May 2017 in “Journal of Cellular Biochemistry” The hairless protein is important for skin, hair, and may influence cancer development.
September 1978 in “PubMed” Chondroitin sulphate is more abundant than hyaluronic acid in skin and hair samples, except in gamma-keratosis.
January 2026 in “Health Food & Biotechnology” A hair serum with 3% keratin from chicken feathers made hair smoother, shinier, and more elastic.
169 citations
,
May 2006 in “Genes & Development” Keratin 17 is crucial for normal hair growth by regulating hair cycle transitions with TNFα.
12 citations
,
October 2007 in “PubMed” Keratin helps protect and strengthen hair, reducing damage and color fading.
13 citations
,
April 1997 in “Biochemical and Biophysical Research Communications” Insulin-dependent diabetes alters hair's molecular structure, making it useful for studying diabetes effects.
17 citations
,
September 2010 in “Pediatric dermatology” A 15-year-old with KID syndrome developed a rare skin condition called PEHFN.
12 citations
,
October 2015 in “Journal of bioactive and compatible polymers” Keratin hydrogel from human hair is a promising biocompatible material for soft tissue fillers.
35 citations
,
June 2012 in “PloS one” Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.
March 2023 in “JAAD case reports” A new genetic change in the keratin 10 gene caused a skin condition called ichthyosis hystrix in a father and his daughter.
3 citations
,
May 2012 in “Journal of Biological Macromolecules” Keratin film can effectively mimic human hair for testing hair damage.
1 citations
,
January 2021 in “Springer Proceedings in Materials” Researchers developed a new method to clearly see and label hair proteins with minimal errors using advanced freezing and microscopy techniques.
1 citations
,
January 1992 in “DNA sequence” Researchers found a non-functional sheep keratin gene due to mutations.
73 citations
,
January 2016 in “International review of cell and molecular biology” Cornification evolved from keratinization in vertebrates, with differences between mammals and sauropsids.
August 1993 in “Journal of Dermatological Science” 1 citations
,
January 2007 in “AIP conference proceedings” High-resolution x-ray images showed three main structures in human hair: medulla, cortex, and cuticle.
September 2025 in “International Journal of Cosmetic Science” Heat and UV exposure damage hair structure by altering keratins.
26 citations
,
May 2001 in “British Journal of Dermatology” Pilomatrixomas likely originate from the hair matrix due to changes in hair keratin expression.
January 2002 in “Proceedings of The Japanese Society of Animal Models for Human Diseases” Keratin2-6g is crucial for hair follicle development, with mutations causing cell degeneration and vacuolation.