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Using 5-α-reductase inhibitors before treatment improves outcomes for patients with metastatic renal cell carcinoma.

Jamogenin and other molecules from plants may help treat hair loss.

Jamogenin and other molecules from plants may help treat hair loss.

Three natural compounds from Ghanaian plants may help treat BPH and alopecia.

Some dibenzo compounds might help treat cancer with fewer side effects.

The discovery of 5α-reductase deficiency in guevedoces led to the development of important urologic medications.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

5 alpha-reductase inhibitors, like finasteride, are used to treat conditions like prostate issues and skin disorders.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction, but the exact reasons are unclear.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.

Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.

A new drug, dutasteride, is at least as effective as the older drug, finasteride, for treating enlarged prostate and may have additional uses.

5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.

Dutasteride effectively treats enlarged prostate with manageable side effects.

5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.

5-alpha-reductase inhibitors may reduce COVID-19 symptoms in bald males.

The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Finasteride and minoxidil together promote hair growth better than either alone.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Finasteride reduces hair growth and is safe for women with excessive hair.

5-alpha reductase inhibitors are generally safe but can cause sexual side effects and require patient education on risks.

Using finasteride or dutasteride does not increase the risk of male breast cancer.

Taking 5-α reductase inhibitors for prostate enlargement or hair loss does not significantly raise the risk of erectile dysfunction.

Rats had lasting erectile problems after stopping a certain medication.

Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.