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A new pain-measuring system using sensors and AI can effectively detect pain in mice, which may help assess pain in humans and develop treatments.

Trichohyalin in hair can trigger immune attacks in alopecia areata.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Human skin can make serotonin and melatonin.

As people age, their hair follicles produce less pigment, leading to gray and white hair, due to factors like reduced enzyme activity and damage to melanocyte DNA.

Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.

Hair grays due to oxidative stress and fewer functioning melanocytes.

In vitro skin models are improving but still need more innovation to fully replicate human skin.

Graying hair happens due to aging and might be delayed by new treatments.

Hair follicle culture helps study cell interactions and effects of substances on tissue growth.

Hair color is determined by melanin produced and transferred in hair follicles.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Genetic factors influence hair traits like shape, color, and greying in Latin Americans.

Hair growth is influenced by dynamic changes in hair follicle cells, which could help treat hair loss.

Thyroid-related genes are active in skin cells and may affect autoimmune conditions.

Alopecia areata is an autoimmune disorder causing hair loss, linked to specific hair follicle antigens and genetic factors.

Cathepsin L is essential for normal hair growth and development.

Hair follicle melanocytes die during hair regression.

We need more research on human hair follicle pigmentation, not just mouse models.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

Cathepsin L deficiency causes large, abnormal cell structures and health issues in mice.

Neuropeptides affect hair growth, with some speeding it up and others slowing it down.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Certain genes control the color of human hair by affecting pigment production.

Researchers developed a quick and easy way to get and grow cells from the base of human hair follicles.

The document concludes that certain rats and mice are useful for studying hair loss in humans and testing treatments.

Group behavior therapy reduces hair-pulling symptoms more than supportive therapy but has limited long-term effectiveness.

Degraded hair shafts resist contamination and can be easily cleaned.