205 citations
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March 2012 in “Science Translational Medicine” PGD2 stops hair growth and is higher in bald men with AGA.
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August 2017 in “Nature cell biology” Lactate production is important for activating hair growth stem cells.
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April 2005 in “The American journal of pathology (Print)” Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.
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June 2010 in “Molecular & cellular proteomics” Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.
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April 2008 in “Cochrane library” Current treatments for alopecia show no significant long-term benefits.
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August 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” The new "differential stripping" method effectively measures how much substance gets into hair follicles.
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December 2007 in “American Journal of Pathology” Stress-related substance P may lead to hair loss and negatively affect hair growth.
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May 2016 in “Nature communications” Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.
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February 2007 in “International Journal of Dermatology” Alopecia areata causes hair loss, has no cure, and various treatments exist.
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September 2012 in “Genes & development” Aging causes skin stem cells to work less effectively.
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June 2012 in “Genes & Development” Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.
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November 1984 in “Journal of the American Academy of Dermatology” No single treatment is consistently effective for alopecia areata, and more research is needed.
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July 2005 in “The FASEB journal” Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.
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August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.
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May 2015 in “European journal of pharmaceutics and biopharmaceutics” The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.
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September 2005 in “Journal of Investigative Dermatology” Applying a special compound can promote hair growth without harmful side effects.
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June 2002 in “The EMBO Journal” Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.
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March 2011 in “Journal of controlled release” New micelle solutions greatly improve skin delivery of certain antifungal drugs.
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July 2004 in “American Journal of Pathology” Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.
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July 2002 in “Molecular and cellular biology” Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.
105 citations
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May 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” Activating TRPV3 stops human hair growth.
103 citations
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November 2014 in “Journal of Cell Biology” MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
102 citations
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July 2007 in “Genes & Development” A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.
102 citations
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February 2008 in “The FASEB Journal” One minoxidil-sensitive potassium channel exists in human hair follicles.
101 citations
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July 2021 in “Nature Communications” 4D polycarbonate scaffolds show promise for soft tissue repair due to their biocompatibility, shape memory, and minimal immune response.
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September 1999 in “British Journal of Dermatology” The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.
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July 2017 in “Clinical Reviews in Allergy & Immunology” New treatments for Alopecia Areata show promise but need to be more effective and affordable.
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September 2017 in “Analytica Chimica Acta” Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.
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April 2007 in “Journal of Investigative Dermatology” Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.
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July 2010 in “Genes & development” Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.