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Did you mean N-Acetylcysteine?

GlossaryN-Acetylcysteine

supplement that replenishes antioxidant glutathione and supports detoxification

N-Acetylcysteine (NAC) is a supplement and medication derived from the amino acid L-cysteine. It is commonly used to help replenish levels of the antioxidant glutathione in the body, support liver detoxification, and treat conditions like acetaminophen overdose and chronic respiratory issues. NAC has also been studied for its potential benefits in promoting hair growth and treating certain types of alopecia due to its antioxidant properties.

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research Into the redox control: N-acetyl-cysteine pleiotropic effects from the laboratory to clinical applications

4 citations , December 2013 in “Acupuncture and related therapies”

N-acetyl-cysteine shows promise in treating various diseases and may improve skin and hair conditions, but more research is needed on dosages and long-term effects.

research Comparison of N-acetyl cysteine with metformin on clinical profile in anovulatory infertile women with PCOS

May 2018 in “International journal of clinical obstetrics and gynaecology”

N-acetyl cysteine and metformin both improved fertility in women with PCOS equally, but N-acetyl cysteine had fewer side effects.

research TRAIL sensitization of PC3 prostate cancer cells by doxorubicin can be blocked by the anti-oxidant N-acetyl-cysteine or by the iron chelator deferoxamine

October 2006 in “Clinical Cancer Research”

Antioxidants can block the cancer-fighting effects of doxorubicin.

research Efficacy and Tolerability of N-Acetyl-Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men

October 2021 in “QJM: An International Journal of Medicine”

N-acetyl-cysteine improves hair growth and is safe for treating early male hair loss.

research N-acetylcysteine in the treatment of trichotillomania

65 citations , January 2012 in “International Journal of Trichology”

N-acetylcysteine may help treat trichotillomania.

research Suppression of uterine and placental ferroptosis by N-acetylcysteine in a rat model of polycystic ovary syndrome

53 citations , November 2021 in “Molecular Human Reproduction”

N-acetylcysteine may help treat uterine and placental issues in PCOS.

Treatment with ImuVert and N-Acetylcysteine Protects Rats from Cyclophosphamide and Cytarabine-Induced Alopecia

research Treatment with ImuVert/JV-Acetylcysteine Protects Rats from Cyclophosphamide/ Cytarabine-Induced Alopecia

26 citations , January 1992 in “Cancer investigation”

N-acetylcysteine and ImuVert can prevent hair loss in rats caused by chemotherapy.

Evidence of Hair Loss After Subacute Exposure to 2-Chloroethyl Ethyl Sulfide, a Mustard Analog, and Beneficial Effects of N-Acetylcysteine

research Evidence of hair loss after subacute exposure to 2-chloroethyl ethyl sulfide, a mustard analog, and beneficial effects ofN-acetyl cysteine

14 citations , January 2004 in “Journal of Biochemical and Molecular Toxicology”

Mustard gas exposure causes hair loss, but treating with N-acetylcysteine can prevent it.

research Comparison of metformin and N-acetylcysteine on metabolic parameters in women with polycystic ovarian syndrome

1 citations , June 2017 in “International journal of reproduction, contraception, obstetrics and gynecology”

N-acetylcysteine was more effective and had fewer side effects than metformin for improving insulin resistance in women with PCOS.

Effect of N-Acetylcysteine on Hair Follicle Changes in Mouse Model of Cyclophosphamide-Induced Alopecia: Histological and Biochemical Study

research Effect of N-acetylcysteine on hair follicle changes in mouse model of cyclophosphamide-induced alopecia: histological and biochemical study

April 2024 in “Histochemistry and cell biology”

N-acetylcysteine may prevent hair loss caused by chemotherapy.

research A case of trichotillomania with bulimia: combined with N-acetylcysteine synergistic therapy

April 2021 in “Research Square (Research Square)”

N-acetylcysteine improved symptoms of trichotillomania and bulimia.

research Influence of FHIT on benzo[ a ]pyrene-induced tumors and alopecia in mice: Chemoprevention by budesonide and N -acetylcysteine

24 citations , May 2006 in “Proceedings of the National Academy of Sciences of the United States of America”

Budesonide and N-acetylcysteine reduced tumors and alopecia in mice, regardless of FHIT gene status.

research Trichotillomania: a good response to treatment with N-acetylcysteine

27 citations , August 2017 in “Anais Brasileiros de Dermatologia”

N-acetylcysteine effectively treats trichotillomania.

research Trichotillomania treated with n-acetylcysteine

3 citations , May 2018 in “Psychiatry and Clinical Psychopharmacology”

N-acetylcysteine may help treat trichotillomania.

research Characterization of the cysteine-rich calcium-binding S100A3 protein from human hair cuticles

17 citations , December 2002 in “Biochemical and biophysical research communications”

Scientists found out how a specific protein in human hair cuticles behaves and is structured.

research Low-Molecular-Weight Synthetic Antioxidants: Classification, Pharmacological Profile, Effectiveness and Trends

9 citations , March 2022 in “Antioxidants”

Synthetic antioxidants are effective, cheap, and stable, with some like zinc and cholecalciferol reducing child and cancer deaths, but the safety of additives like BHA, BHT, TBHQ, and PEG needs more research.

research Trichotillomania

219 citations , September 2016 in “American Journal of Psychiatry”

Trichotillomania is different from OCD and is best treated with habit reversal therapy and specific medications.

research Particulate matter 2.5 damages skin cells by inducing oxidative stress, subcellular organelle dysfunction, and apoptosis

215 citations , March 2018 in “Archives of Toxicology”

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

research Polycystic Ovary Syndrome: A Comprehensive Review of Pathogenesis, Management, and Drug Repurposing

68 citations , January 2022 in “International Journal of Molecular Sciences”

PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.

Induction of Transforming Growth Factor-Beta 1 by Androgen Is Mediated by Reactive Oxygen Species in Hair Follicle Dermal Papilla Cells

research Induction of transforming growth factor-beta 1 by androgen is mediated by reactive oxygen species in hair follicle dermal papilla cells

56 citations , September 2013 in “Journal of Biochemistry and Molecular Biology”

Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.

research Pharmacotherapy of polycystic ovary syndrome - an update

34 citations , January 2011 in “Fundamental & Clinical Pharmacology”

New treatments for PCOS show promise, but no current medication treats all aspects of the condition.

research Monilethrix: A rare hereditary condition

12 citations , January 2013 in “Indian Journal of Dermatology”

Monilethrix is a rare genetic hair disorder that's hard to treat.

research Prostaglandin D2 Uses Components of ROS Signaling to Enhance Testosterone Production in Keratinocytes

9 citations , September 2017 in “Journal of Investigative Dermatology Symposium Proceedings”

Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, and antioxidants may help treat hair loss.

research BMI1 is required for melanocyte stem cell maintenance and hair pigmentation

4 citations , May 2023 in “Pigment Cell & Melanoma Research”

BMI1 is essential for preventing hair greying and maintaining hair color.

research Diagnosis and treatment of trichotillomania

3 citations , April 2011 in “Neuropsychiatry”

Behavioral therapy, N-acetyl cysteine, and olanzapine may help treat trichotillomania.

research Hirsutism: Diagnosis and Treatment

2 citations , January 2012 in “Journal of metabolic syndrome”

The document concludes that hirsutism can be managed with various treatments tailored to the individual, potentially improving quality of life.

research A case of trichotillomania presenting as a factitious ulcer

January 2023 in “Odisha Journal of Psychiatry”

Thorough patient interviews are crucial to identify self-inflicted hair loss.

research Effect of Minoxidil on Trabecular Outflow via the Paracellular Pathway

January 2020 in “Korean journal of ophthalmology/Korean Journal of Ophthalmology”

Minoxidil increases cell layer permeability by reducing tight junction proteins and raising ROS levels.

research Trichotillomania and Traction Alopecia

May 2017 in “InTech eBooks”

Hair pulling disorder is treated with therapy and medication; hair loss from tension can be reversed if caught early.

research Trichotillomania.

April 2016 in “Apollo (University of Cambridge)”

Trichotillomania is a hair-pulling disorder needing different treatments than OCD.