55 citations
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October 1975 in “Circulation” Minoxidil, propranolol, and furosemide effectively control severe hypertension, but may cause sodium retention.
49 citations
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January 2004 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.
50 citations
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September 1975 in “American Heart Journal” Minoxidil effectively controls blood pressure in severe cases, but may cause fluid retention and edema.
July 2018 in “Reactions Weekly” Lower finasteride doses had more side effects; dutasteride caused back pain; more research needed on post-finasteride syndrome.
May 2024 in “International journal of medicine and psychology.” Yuperio combined with bisoprolol improves heart function in patients with dilated cardiomyopathy.
May 2015 in “Journal of The American Academy of Dermatology” Finasteride for hair loss in young men increases the risk of sexual dysfunction.
34 citations
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April 2006 in “PubMed” Tamsulosin is a cost-effective treatment for BPH symptoms.
May 2003 in “Hair transplant forum international” Strontium can effectively reduce skin irritation and inflammation.
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December 1997 in “Clinical Endocrinology” Spironolactone may help reduce hair loss in androgenic alopecia.
September 2023 in “Journal of the American Academy of Dermatology” The cleanser gel significantly reduces facial oiliness.
November 2013 in “The Journal of Urology”
August 2025 in “medRxiv (Cold Spring Harbor Laboratory)” 5-alpha reductase inhibitors may increase depression risk by 31%, but results vary based on comparison groups.
1 citations
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January 2011 in “Brunel University Research Archive (BURA) (Brunel University London)” Dutasteride likely doesn't harm wild fish due to low environmental levels, but more research is needed on bioaccumulation.
48 citations
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November 2017 in “Journal of the American Academy of Dermatology” Tofacitinib 2% ointment helped hair regrow in 3 out of 10 patients with alopecia areata, but caused side effects like scalp irritation and raised cholesterol in some.
February 2026 in “Mendeley Data” Using 5-alpha reductase inhibitors may lower prostate cancer risk in people with androgenetic alopecia.
April 2024 in “Expert opinion on emerging drugs” New treatments for male hair loss are being explored to improve effectiveness and reduce side effects.
September 2022 in “Concilium” Scalp cooling effectively prevents chemotherapy-induced hair loss but requires better pain management.
3 citations
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January 2022 in “Precision medicine and clinical omics” Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.
August 2009 in “Australian Prescriber” Dutasteride is approved to help manage prostate enlargement.
20 citations
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July 1990 in “Journal of the American Academy of Dermatology” Captopril may cause hair loss, as shown by a woman's hair regrowing after stopping the medication.
2 citations
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January 2012 in “Hair therapy & transplantation” DDAIP-HCl significantly increases minoxidil absorption into the skin.
January 2015 in “Вестник дерматологии и венерологии” Some treatments like minoxidil, finasteride, and dutasteride are effective for hair loss, but there's no agreed best treatment.
23 citations
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January 1998 in “Urological research” Castration and finasteride lower urinary oxalate in male rats, potentially treating urolithiasis.
12 citations
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June 2001 in “Bioorganic & Medicinal Chemistry” Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.
5 citations
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January 2021 in “Journal of Cosmetic Dermatology” Topical cetirizine 1% promotes hair growth in male androgenetic alopecia patients.
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January 1994 in “Annual Reports in Medicinal Chemistry” Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.
3 citations
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May 2017 in “Bioorganic & medicinal chemistry letters” New compounds were made that are promising for prostate cancer therapy.
22 citations
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February 2002 in “Planta Medica” Compounds from Angelica koreana roots, especially osthenol, could be effective for treating conditions like prostate disease and hair loss.