41 citations
,
June 2010 in “Anais Brasileiros de Dermatologia” Isotretinoin is safe and effective for acne, with common side effects like dry lips; serious side effects are rare.
40 citations
,
July 2008 in “PROTEOMICS” A new model helps study acne and test treatments.
40 citations
,
May 2010 in “American Journal of Clinical Dermatology” AKN might be a skin marker for metabolic syndrome.
39 citations
,
January 2018 in “British journal of dermatology/British journal of dermatology, Supplement” Acne and hidradenitis suppurativa have different causes and risk factors, but both are driven by inflammation and may benefit from treatments targeting interleukin-1.
39 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
39 citations
,
May 2011 in “Human Immunology” Genetics play a role in acne, but how exactly they contribute is not fully understood.
39 citations
,
January 1980 in “Dermatology” Cyproterone acetate was effective in treating acne, hirsutism, and alopecia with few side effects.
37 citations
,
January 2013 in “Postepy Dermatologii I Alergologii” Isotretinoin effectively reduces acne but causes dry skin, higher skin pH, more redness, and hair loss.
37 citations
,
September 2005 in “Australasian Journal of Dermatology” A man with scalp and neck skin issues improved after a year of oral isotretinoin.
35 citations
,
March 2012 in “Journal of dermatological science” The document concludes that advanced methods show the presence of P. acnes in acne lesions but do not prove it causes acne.
35 citations
,
January 2008 in “American Journal of Clinical Dermatology” KFSD can be linked to acne keloidalis nuchae and tufted hair folliculitis.
33 citations
,
April 2021 in “Journal of Dermatological Treatment” New ways to treat acne are being discovered.
31 citations
,
June 2015 in “British Journal of Dermatology” Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.
31 citations
,
December 2010 in “International Journal of Andrology” Men with testicular cancer were less likely to experience baldness and severe acne.
30 citations
,
June 2015 in “British Journal of Dermatology” Acne is common in women, often hormone-related, negatively affects quality of life, and requires various treatments.
29 citations
,
January 2016 in “Disease Markers” Survivin and IGF-I may play a role in acne and scarring.
29 citations
,
January 2007 in “Dermatologic Clinics” Photodynamic Therapy is an effective treatment for mild to severe acne.
29 citations
,
January 1998 in “Dermatology” Many acne patients have high androgen levels, which may lead to PCOD, but treatments like oral contraceptives and antiandrogens can help.
29 citations
,
March 2023 in “European Journal of Human Genetics” New genetic factors linked to acne risk were discovered, highlighting the role of certain pathways and genes.
29 citations
,
March 2017 in “International Journal of Women's Dermatology” Hormone therapies like birth control pills and spironolactone are safe and effective for treating women's adult acne.
29 citations
,
January 2016 in “Experimental Dermatology” Mechanical stress may cause lesions in Hidradenitis suppurativa.
27 citations
,
June 2017 in “International Journal of Dermatology” The study suggests that acne keloidalis nuchae is linked to conditions like pseudofolliculitis barbae, scalp infections, metabolic syndrome, and is more common in males with an average onset age of 25.4 years.
24 citations
,
March 2018 in “Pediatric Dermatology” Testosterone treatment in transgender teens can worsen acne, requiring careful treatment due to mental health and medication side effects.
24 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.
24 citations
,
December 1988 in “British Journal of Dermatology” Acne severity in women may not be linked to increased male hormone indicators like excess body hair, menstrual irregularities, or hair loss.
24 citations
,
June 2008 in “Journal of Cutaneous Pathology” The exact cause of hidradenitis suppurativa is still unknown.
24 citations
,
October 2007 in “Clinical and experimental dermatology” Surgical excision with natural healing effectively treats acne keloidalis nuchae without recurrence.
22 citations
,
September 2019 in “Trends in Immunology” Acne is a temporary skin imbalance during puberty that often resolves on its own.
22 citations
,
January 2017 in “Dermatology” Spironolactone is effective and safe for treating acne with minimal side effects.
21 citations
,
January 2017 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” Acne is an important sign of androgen excess disorders in women.