27 citations
,
January 2012 in “Current Topics in Microbiology and Immunology” Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.
23 citations
,
September 2018 in “Journal of Investigative Dermatology” A hydrogel made from pig fat helps wounds heal faster by regenerating skin fat cells.
19 citations
,
January 2017 in “Stem Cells International” Adipose-derived stem cells show promise in treating skin conditions like vitiligo, alopecia, and nonhealing wounds.
17 citations
,
February 2015 in “International Journal of Molecular Sciences” A special mix from certain skin cells can help hair grow by making hair root cells grow faster and activating growth signals.
9 citations
,
July 2018 in “Current Pharmaceutical Design” HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.
8 citations
,
February 2013 in “Central European Journal of Biology” Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.
7 citations
,
March 2018 in “Asian-Australasian journal of animal sciences” OCIAD2 and DCN genes affect hair growth in goats by having opposite effects on a growth signaling pathway and inhibiting each other.
5 citations
,
August 2020 in “Stem Cell Research & Therapy” Using fat-derived stem cells with the drug meglumine antimoniate can help control skin disease and reduce parasites in mice with leishmaniasis.
4 citations
,
October 2025 in “International Journal of Medical Sciences” Tripeptides help heal wounds and regenerate skin by speeding up tissue repair and reducing inflammation.
4 citations
,
March 2017 in “Development” Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.
3 citations
,
July 2025 in “International Journal of Biological Sciences” m6A methylation is crucial for proper wound healing and tissue repair.
3 citations
,
January 2011 in “Annals of Dermatology” Blocking EGFR in skin cells doesn't majorly increase inflammation markers.
January 2026 in “BioScience Trends” UV radiation causes skin aging by damaging cells and triggering harmful processes.
June 2008 in “Dermatologic Surgery” Hydrogen peroxide may have both positive and negative effects on wound healing, and its safe concentration for hair transplant surgery is unclear.
163 citations
,
March 2012 in “BMC biology” Stem cell niches support, regulate, and coordinate stem cell functions.
129 citations
,
May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
89 citations
,
January 2009 in “Advances in Clinical Chemistry” Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.
39 citations
,
May 2014 in “Frontiers in Pharmacology” Special immune cells called Tregs can help prevent lung scarring by blocking a specific growth factor.
33 citations
,
January 2022 in “Scientific Reports” The method improved CoQ10's stability and effectiveness for anti-ageing skincare.
27 citations
,
July 2017 in “Facial Plastic Surgery” Platelet-Rich Plasma (PRP) shows promise for hair growth and skin improvement in aesthetic surgery.
21 citations
,
November 2022 in “Frontiers in immunology” Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
14 citations
,
July 2021 in “Biomolecules” Centipeda minima extract helps hair grow by activating important growth signals and could be a promising hair loss treatment.
11 citations
,
July 2021 in “Nanomaterials” Wound covers with α-13'-COOH from vitamin E can improve and speed up wound healing.
11 citations
,
January 2013 in “Postępy Dermatologii i Alergologii” The conclusion is that a combination of noninvasive treatments and lifestyle changes can improve skin health during menopause.
5 citations
,
February 2024 in “Frontiers in bioengineering and biotechnology” Electrospun scaffolds can improve healing in diabetic wounds.
3 citations
,
August 2014 in “Cellular reprogramming” Hair follicle stem cells need all reprogramming factors to become pluripotent.
2 citations
,
May 2023 in “Frontiers in immunology” Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.
March 2026 in “Frontiers in Medicine” Different types of alopecia cause hair loss due to immune system issues, with some allowing regrowth and others causing permanent loss.
PmtHEE is a better model for studying pigmented skin because it includes melanocytes and shows improved cell differentiation.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Early regulatory T cells are crucial for normal skin pigmentation.