September 2017 in “Journal of Investigative Dermatology” Hair care products used for 4 weeks made hair smoother.
April 2016 in “Journal of Investigative Dermatology” Male pattern baldness is linked to a higher risk of certain skin cancers, especially on the scalp.
April 2016 in “Journal of Investigative Dermatology” SOX4 is crucial for the development of melanoma.
August 2012 in “Nature Cell Biology” A pathway helps maintain long telomeres in both stem and cancer cells.
August 2012 in “Nature Cell Biology” The tumor suppressor BRCA2 helps in cell division by bringing key proteins to the area where cells split.
September 2008 in “Fertility and Sterility” Exposure to fatty acids significantly increased androgen levels in female dogs, suggesting a link to conditions like insulin resistance and PCOS.
April 2018 in “Journal of Investigative Dermatology”
370 citations
,
September 1999 in “The New England Journal of Medicine” Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.
248 citations
,
December 2011 in “Journal of Neuroscience” Neurosteroids are crucial for stress response, and targeting specific receptors may help treat certain disorders.
218 citations
,
October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.
165 citations
,
January 2014 in “Dermatology Research and Practice” Zinc is effective for treating various skin conditions, including warts and acne.
123 citations
,
September 1987 in “JAMA” IL-2 treatment causes skin eruptions and other reversible side effects, and may play a role in psoriasis.
111 citations
,
June 2002 in “The EMBO Journal” Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.
87 citations
,
July 2007 in “British Journal Of Nutrition” Lactococcus lactis strain H61 may reduce some ageing symptoms.
77 citations
,
March 2021 in “Nature” Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.
76 citations
,
April 2013 in “PLoS ONE” Chronic stress can cause hair loss by increasing oxidative stress, but antioxidants may help.
71 citations
,
May 2007 in “The FASEB journal” Human hair follicles produce and respond to erythropoietin, helping protect against stress.
66 citations
,
June 2006 in “Journal of The American Academy of Dermatology” Finasteride increases hair weight and count in men with hair loss, with best results after four years.
61 citations
,
April 2014 in “Radiation Research” RTA 408 cream protects mice from radiation skin damage.
60 citations
,
January 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Applying a specific inhibitor lightens skin and hair color.
51 citations
,
February 2009 in “Journal of dermatological science” Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.
49 citations
,
August 2016 in “Aesthetic Surgery Journal” Micro-needling effectively improves wrinkles, scars, and hair growth, but proper technique and safety are important.
49 citations
,
April 2003 in “Biomaterials” Bismuth subgallate and borneol together improve skin wound healing better than when used separately or compared to other treatments.
48 citations
,
January 2024 in “Immune Network” IL-15 is key for T cell function and could help improve treatments for immune-related diseases.
48 citations
,
June 2013 in “Journal of Dermatological Science” Valproic acid may help hair grow and could be a safe treatment for hair loss.
44 citations
,
April 2006 in “Expert opinion on drug safety” Gefitinib can cause skin problems, diarrhea, and nausea, but rarely causes severe lung disease or hair loss.
42 citations
,
December 2014 in “Clinical, cosmetic and investigational dermatology” Nonablative radiofrequency treatments, especially microneedle and fractional types, can improve acne scars by 25%–75% after 3-4 sessions, with full results in 3 months and some side effects.
42 citations
,
April 2012 in “Seminars in Oncology” Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.
41 citations
,
April 2012 in “Journal of The European Academy of Dermatology and Venereology” Dutasteride-containing mesotherapy effectively treats female hair loss, improving density and thickness with minimal side effects.
39 citations
,
March 2008 in “Growth hormone & IGF research” Raspberry ketone may help grow hair and improve skin elasticity.