research Protective effects of finasteride on the pulmonary immune response in a combined model of trauma-hemorrhage and polymicrobial sepsis in mice
Finasteride helps reduce lung inflammation and damage after trauma and infection.
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research A Case Study on Exploring Immune Dysregulation in Alopecia Areata - Mechanisms and Treatments Outcomes
Individualized treatment and psychological support improved the patient's quality of life and appearance despite medication side effects.
research Extra Virgin Olive Oil as Nutritional Therapeutic Immuno-Enhancer
Extra virgin olive oil may boost the immune system and help fight infections like COVID-19.
research Therapeutic small extracellular vesicles from key human stem and immune cellular sources: A review
Small extracellular vesicles from stem and immune cells show promise for treating various diseases but face challenges in clinical use.
research Systemic Circulating Leptin – Aiding New Dimension of Immune-Related Skin Carcinogenesis and Lipid Metabolism
High leptin levels may promote skin cancer and inflammation, suggesting potential for leptin-targeted therapies.
research Mechanisms of tolerance and potential therapeutic interventions in Alopecia Areata
Targeting immune tolerance issues in Alopecia Areata could restore hair growth and maintain remission.
research Recent advances and challenges in 3D bioprinting for skin tissue regeneration
3D bioprinting shows promise for skin regeneration but needs more development to fully replicate natural skin.
research Urticaria Neonatorum: Accumulation of tryptase‐expressing mast cells in the skin lesions of newborns with Erythema Toxicum
Newborns with the common rash Erythema Toxicum have many active mast cells in their skin, but these cells don't produce the LL-37 peptide.
research Mechanism of PPARα agonist in alopecia areata
PPARα agonists may help treat alopecia areata by reducing inflammation.
research Regulatory T cells in skin
Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.
research Age-associated inflammation connects RAS-induced senescence to stem cell dysfunction and epidermal malignancy
Older skin has higher cancer risk due to inflammation and stem cell issues.
research Tissue resident and follicular Treg cell differentiation is regulated by CRAC channels
CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.
research New insights into inflammatory memory of epidermal stem cells
Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.
research Langerin+ Dendritic Cells in Cutaneous Fibrosis: The TGF-β1 Signaling Axis
Targeting specific cell interactions may help treat skin fibrosis.
research Integrated-omics profiling unveils the disparities of host defense to ECM scaffolds during wound healing in aged individuals
Aged individuals heal wounds less effectively due to specific immune cell issues.
research Stress exposure modulates peptidergic innervation and degranulates mast cells in murine skin
Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.
research Skin Commensal Antigens: Taking the Road Less Traveled
Skin bacteria can help wound healing by activating certain immune cells.
research Study ofDemodexmites: Challenges and Solutions
The conclusion is that a new biopsy technique and humidity chamber help study skin mites better and suggest mite overpopulation may cause skin diseases.
research Alopecia areata: a review of disease pathogenesis
Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.
research Effects of Imiquimod on Hair Follicle Stem Cells and Hair Cycle Progression
Imiquimod cream activates hair follicle stem cells and causes early hair growth by changing immune cells and certain protein expressions.
research The therapeutic potential of CRTH2/DP2 beyond allergy and asthma
CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.
research Fractional Laser-assisted Hair Regrowth and Microneedling for the Treatment of Alopecia Areata: A Review
Fractional lasers and microneedling, combined with topical agents, could potentially treat Alopecia Areata effectively, but more research is needed due to limited data.
research Alopecia areata multiplex following autologous dermal micrograft injection for treatment of androgenetic alopecia
Hair loss treatment caused more hair loss in a man.
research RANK as a therapeutic target in cancer
RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.
research Regulatory T Cells: the Many Faces of Foxp3
Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.
research TRP Channels in Skin Biology and Pathophysiology
TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
research Choreographing Immunity in the Skin Epithelial Barrier
The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.
research Skin: Basic Structure and Function
The skin is a complex barrier that protects the body, regulates temperature, and helps with immune responses.
research Perforins Expression by Cutaneous Gamma Delta T Cells
Gamma delta T cells in the skin help with healing and defense but can also cause autoimmune issues, and more research is needed to understand how they are activated.
research The Function and Structure of the Skin
The skin protects the body, regulates temperature, senses touch, and makes vitamin D.