research Updated Treatment for Acne: Targeted Therapy Based on Pathogenesis
Future acne treatments should aggressively target inflammation to prevent scarring.
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research Stress-related skin disorders
Stress can worsen skin conditions by affecting hormone levels and immune response.
research A Keratinocyte-specific Epoxygenase, CYP2B12, Metabolizes Arachidonic Acid with Unusual Selectivity, Producing a Single Major Epoxyeicosatrienoic Acid
CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.
research Skin steroidogenesis in health and disease
The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
research Basics of androgen synthesis and action
Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.
research Cardiovascular risk factors and events in women with androgen excess
Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.
research Clinical relevance of testosterone and dihydrotestosterone metabolism in women
Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.
research Hormonal therapies for acne
Hormonal treatments can improve acne, but they come with potential side effects and risks.
research Hormone therapy in acne
Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.
research Sebaceous immunobiology - skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations
Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
research The Transmembrane Serine Protease HAT-like 4 Is Important for Epidermal Barrier Function to Prevent Body Fluid Loss
HAT-L4 is crucial for preventing body fluid loss by maintaining skin barrier integrity.
research Polycystic ovary syndrome and the differential diagnosis of hyperandrogenism
The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.
research Targets to treat androgen excess in polycystic ovary syndrome
The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
research Melatonin induces a stimulatory action on the scrotal skin components of Soay ram in the non-breeding season
Melatonin stimulates the skin components of ram's scrotum during their non-breeding season.
research Metabolic dysfunction in female mice with disruption of 5α-reductase 1
Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.
research Bad Hair Day: Testosterone and Wnts
Testosterone can both promote hair growth and cause baldness by affecting hair growth signals.
research Goat hair as a bioindicator of environmental contaminants and adrenal activation during vertical transhumance
Goat hair shows changes in metal levels and stress when goats move from indoors to mountain pastures.
research Adrenal and Gonadal Activity, Androgen Concentrations, and Adult Height Outcomes in Boys With Silver-Russell Syndrome
Higher androgen levels during puberty are linked to shorter adult height in boys with Silver-Russell syndrome.
research Generalised Glucocorticoid Resistance
Generalized glucocorticoid resistance causes hormone imbalances and varied symptoms due to gene mutations.
research Pathogenesis and causes of hirsutism
Hirsutism is mainly caused by high androgen levels or sensitivity, with PCOS being the most common cause.
research Androgen excess: a hallmark of polycystic ovary syndrome
Excess androgens may cause PCOS, not just be a symptom.
research Hair Cortisol Is a Potential Indicator of Adrenal Insufficiency in Individuals with Sickle Cell Disease
Hair cortisol may help identify adrenal insufficiency in sickle cell disease patients.
research WNT10B (wingless-type MMTV integration site family)
WNT10B is linked to cancer development and affects survival and disease progression in various cancers.
research Pathologies of the skin and its appendages in endocrine diseases
Endocrine disorders can cause various skin and hair issues.
research Hormonal acne: leading to a paradigm shift in the management of acne
The article concludes that hormonal therapy is an effective long-term acne treatment, even for those without hormonal imbalances.
research Modelling androgen synthesis and action during human sexual differentiation
Male sexual differentiation is regulated independently, while female differentiation occurs in an androgenic environment, affecting conditions like congenital adrenal hyperplasia.
research STUDIED ON TOXICITY OF HYDROCORTISONE 17-BUTYRATE 21-PROPIONATE : 6. Subacute Toxicity in Dogs by Percutaneous Adminisration
Hydrocortisone 17-butyrate 21-propionate ointment caused reversible side effects like skin issues, weight gain, and organ changes in dogs.
research Hidradenitis suppurativa: pathogenesis and management
Hidradenitis suppurativa, a chronic skin disease, can be managed with antibiotics, lifestyle changes, and in severe cases, surgery. Early diagnosis and careful planning are key, and laser treatment can be an efficient solution for mild to severe cases.
research “Sebocytes’ makeup” - Novel mechanisms and concepts in the physiology of the human sebaceous glands
Hormones and signaling pathways control sebaceous gland function and could help treat acne.
research ACNE
Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.