59 citations
,
May 2014 in “Expert Opinion on Therapeutic Targets” The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
49 citations
,
November 2019 in “Egyptian Journal of Medical Human Genetics” Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.
47 citations
,
February 2015 in “European Journal of Clinical Investigation” The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.
42 citations
,
July 2015 in “Journal of The American Academy of Dermatology” The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.
42 citations
,
January 2011 in “European Journal of Dermatology” Early balding men may have insulin resistance, but lifestyle changes can help.
40 citations
,
May 2014 in “PLoS ONE” Chronic stress can reduce skin pigmentation.
37 citations
,
June 2021 in “Journal of the European Academy of Dermatology and Venereology” Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.
34 citations
,
July 2020 in “Frontiers in immunology” Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.
32 citations
,
November 2011 in “Reproductive Sciences” Brazilian women with PCOS and both menstrual irregularity and high male hormone levels have a higher chance of having metabolic syndrome.
27 citations
,
August 2018 in “Therapeutic Delivery” Nanotechnology could make hair loss treatments more effective and reduce side effects, but more research is needed before it's available.
26 citations
,
February 2009 in “Drug Development Research” 17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.
25 citations
,
June 2019 in “Endocrine Related Cancer” Mutations in certain receptors can cause diseases and offer new treatment options.
20 citations
,
March 2017 in “Reproductive Biology and Endocrinology” Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.
19 citations
,
September 2010 in “The American journal of pathology” High glucocorticoids cause pancreatic malfunction and malabsorption, reversible with enzyme supplements.
15 citations
,
June 2020 in “Experimental Dermatology” Hormones and genes affect hair growth and male baldness.
13 citations
,
September 2020 in “International Journal of Molecular Sciences” PRP therapy and minoxidil combo works best for male hair loss.
12 citations
,
January 1978 Friesian heifers take about 18 months to adapt to Kenya's climate, with hair changes not strongly linked to weight gain.
11 citations
,
November 2017 in “Electronic physician” Depression severity is not linked to PCOS markers like BMI, insulin resistance, or testosterone levels.
11 citations
,
August 2009 in “Expert Opinion on Drug Discovery” We need better ways to test and understand SARMs to make safer and more effective treatments.
9 citations
,
December 1978 in “Australian Journal of Biological Sciences” Flumethasone causes wool shedding in Merino wethers, with recovery in about 60 days.
8 citations
,
May 2017 in “Chinese Journal of Integrative Medicine” Miscanthus sinensis flower extract may help promote hair growth and prevent hair loss.
7 citations
,
March 2011 in “Expert Opinion on Drug Safety” Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.
6 citations
,
October 2024 in “npj Digital Medicine” Long-COVID causes more health issues after COVID-19, varying by age, sex, and infection wave.
6 citations
,
May 2022 in “Research and reports in urology” Caesalpinia bonduc seed extracts may help treat enlarged prostate in rats.
5 citations
,
January 2024 in “Journal of Cancer” The treatment combination is effective and generally safe for lung cancer.
4 citations
,
February 2019 in “Biological Trace Element Research” Chromium salts may help with insulin sensitivity in PCOS, but more research is needed to confirm their overall effectiveness and safety.
4 citations
,
April 2016 in “Journal of Dermatology Research and Therapy” Anti-androgens are safe and effective for treating moderate to severe adult female acne.
3 citations
,
April 2015 in “American journal of biomedical sciences” Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.
3 citations
,
February 2005 in “Expert Opinion on Investigational Drugs” New treatments for hair loss are being developed using molecular biology.
2 citations
,
March 2025 in “Archives of Dermatological Research” HEV light can harm or help skin and scalp, so safe exposure guidelines are needed.