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Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.

Flutamide works better than finasteride for hirsutism, and combining both is slightly better but not much.

Low-dose finasteride effectively reduces hirsutism without serious side-effects.

The enzyme PST is found in developing human kidneys and helps with detoxification and development.

Itraconazole helps improve tough skin infections but may not prevent them from coming back.

Surgery to lower high testosterone in postmenopausal women with certain ovarian tumors doesn't significantly affect their metabolism.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.