March 2026 in “Calcified Tissue International” The EDA pathway plays a key role in bone development by interacting with other signaling pathways.
November 2023 in “Journal of Investigative Dermatology”
April 2021 in “Journal of Investigative Dermatology” People with atopic dermatitis have more CD4+ T cells that respond to a certain bacterial lipid, which may play a role in the skin condition's inflammation.
4 citations
,
February 1953 in “Experimental biology and medicine” Adrenocortical extract is less effective at stopping hair growth in young rats than in adult rats.
4 citations
,
December 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Overactive Wnt signaling in mouse skin stem cells causes acne-like cysts and shrinking oil glands, which some treatments can partially fix.
9 citations
,
July 2020 in “Cell Proliferation” Epiregulin can help hair grow and may be useful for treating hair loss.
July 2024 in “Journal of Investigative Dermatology” Allergic contact dermatitis may promote hair growth by activating hair follicle stem cells.
19 citations
,
August 2019 in “Journal of Cellular Biochemistry” ADSCs help protect skin from UV damage and aging.
226 citations
,
August 2006 in “Molecular and Cellular Biology” EGF signaling affects gene expression in skin cells, influencing hair growth and potentially cancer.
September 2023 in “Frontiers in Medicine” The scalp fat tissue of men with hair loss shows changes in gene activity that may contribute to their condition.
12 citations
,
June 2019 in “Psychoneuroendocrinology” Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.
January 2022 in “Current Enzyme Inhibition” New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.
7 citations
,
December 2021 in “Archives of Dermatological Research” Adiponectin reduces hair pigmentation and affects hair growth signals.
February 2025 in “Science Advances” Wnt signaling helps regenerate hair follicles by affecting how skin cells sense and respond to mechanical forces.
46 citations
,
November 2019 in “Journal of Integrative Plant Biology” CaM7 and CNGC14 interaction controls root hair growth in Arabidopsis.
5 citations
,
February 2014 in “PloS one” Eyelid cells share signaling components but differ in pathway activity.
56 citations
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November 2007 in “Molecular and cellular endocrinology” Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.
6 citations
,
June 2021 in “The Journal of Experimental Medicine” Understanding signaling in blood cells is complex and still limited.
9 citations
,
March 2019 in “Molecular & cellular proteomics” Reductive stress messes up collagen balance and alters cell signaling in human skin cells, which could help treat certain skin diseases.
1 citations
,
January 2025 in “Journal of Cosmetic Dermatology” Inhibiting ACE2 improves skin regeneration during tissue expansion.
6 citations
,
November 2022 in “Antioxidants” OR2AT4 helps reduce aging and cell damage in human skin cells.
August 2023 in “Frontiers in Oncology” New drugs and therapies targeting specific pathways show promise in treating advanced prostate cancer.
20 citations
,
January 2021 in “Plants” High energy boosts root hair growth in plants, while low energy stops it.
3 citations
,
June 2024 in “iScience” Axolotl spinal cord regeneration may be controlled by a specific signal affecting cell sensitivity and diffusion.
43 citations
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January 2016 in “Cellular physiology and biochemistry” Epidermal Growth Factor helps hair follicle cells grow and move by activating a specific cell signaling pathway.
66 citations
,
January 2008 in “Pharmacology Biochemistry and Behavior” AC-5216 reduces anxiety in mice through neurosteroids affecting GABAA receptors.
11 citations
,
June 2017 in “Journal of cell science” AGD1's PH domain is essential for its role in root hair growth and polarity.
18 citations
,
February 2018 in “International Journal of Molecular Sciences” PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.
52 citations
,
May 2011 in “Journal of Neuroendocrinology” PEA boosts allopregnanolone production and reduces oxidative stress in brain cells.
50 citations
,
March 2004 in “Trends in Plant Science” NADPH oxidase and phospholipase D help root hairs grow by activating calcium channels.