July 1980 in “Journal of The American Academy of Dermatology” The conference concluded that understanding hair and nail disorders is important, iron deficiency may be linked to hair loss, and while some treatments for skin conditions are effective, they may have risks and high costs.
January 1977 in “Case Reports in Medicine” Steroid cell tumors in the ovary are rare, can produce testosterone causing symptoms, and are mainly treated with surgery.
May 2021 in “Lasers in Surgery and Medicine” Minoxidil and photobiomodulation together improve hair growth better than minoxidil alone.
February 2018 in “The Journal of Sexual Medicine” DA-9401 protects against hair loss, improves organ function, and prevents infertility caused by finasteride.
2 citations
,
May 2023 in “Al Mustansiriyah Journal of Pharmaceutical Sciences” Pterostilbene significantly reduces prostate enlargement and has strong antioxidant effects.
1540 citations
,
October 2008 in “Fertility and Sterility” The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.
991 citations
,
January 2011 in “Nature Reviews Endocrinology” The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.
658 citations
,
June 2003 in “Endocrine reviews” Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.
475 citations
,
January 2016 in “International Review of Psychiatry” The document concludes that non-binary individuals need compassionate support and recognition in healthcare, without being pathologized.
418 citations
,
June 2003 in “Endocrine Reviews” While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.
249 citations
,
November 2003 in “Clinical endocrinology” Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.
223 citations
,
December 2010 in “The Journal of Sexual Medicine” Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.
198 citations
,
July 2011 in “Cochrane library” Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.
182 citations
,
October 2003 in “British Journal of Dermatology” The 2003 guidelines suggest that while some treatments can regrow hair in alopecia areata, none alter the disease's progression, and wigs may be the best option for extensive hair loss.
176 citations
,
August 2015 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.
172 citations
,
November 1983 in “Journal of The American Academy of Dermatology” Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.
165 citations
,
December 2002 in “Molecular and Cellular Endocrinology” Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.
158 citations
,
January 2015 in “Artificial Intelligence in Medicine” DrugNet effectively identifies new uses for existing drugs and may save resources in drug development.
139 citations
,
December 2020 in “Cell Stem Cell” Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
139 citations
,
August 2018 in “Development” The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.
126 citations
,
October 1983 in “Journal of The American Academy of Dermatology” Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.
118 citations
,
April 1998 in “Dermatologic Clinics” Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.
112 citations
,
January 2014 in “Molecular and cellular therapies” Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
109 citations
,
January 2011 in “Frontiers in Systems Neuroscience” Choosing the right model order in brain connectivity analysis can affect the detection of differences between healthy individuals and those with seasonal affective disorder.
90 citations
,
October 1996 in “Dermatologic Clinics” Growth factors are crucial for hair development and could help treat hair diseases.
89 citations
,
November 2014 in “Medical Clinics of North America” Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.
83 citations
,
June 2018 in “Frontiers in immunology” Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.
82 citations
,
October 2019 in “Frontiers in Immunology” Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.
71 citations
,
March 2009 in “Seminars in cutaneous medicine and surgery” Alopecia areata can cause unpredictable hair loss, and treatments like corticosteroids and minoxidil may help but have varying side effects.
71 citations
,
June 2006 in “Human Reproduction” Women with PCOS who have low SHBG are more likely to have low good cholesterol and metabolic syndrome.