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A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Hormonal treatment in transgender women reduces semen quality, but stopping treatment may improve it.

LGBT individuals have unique skin health needs, including higher STD risks and side effects from gender-affirming treatments, requiring dermatologists to offer knowledgeable and culturally competent care.

Diphencyprone (DPC) is an effective and safe long-term treatment for alopecia areata, especially with maintenance therapy.

Gender-affirming hormone therapy affects health risks and requires careful management, especially as transgender individuals age.

Understanding sex and gender differences can improve personalized dermatology care.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Transmasculine individuals on testosterone therapy need tailored contraception and fertility advice due to unique risks and benefits of each contraceptive method.

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

Healthcare providers need better understanding and cultural sensitivity to improve care for transgender patients with kidney failure needing transplants.

AGA treatments like minoxidil and LLLLT are safe and effective for gender minority patients.

Hair absorbs molecules differently based on their size, charge, and love for water, and less at higher pH; this can help make better hair products.

Transgender and nonbinary individuals experience hair loss, with transmen on testosterone seeing more severe hair loss, while feminizing hormones may stabilize hair loss in transwomen.

Transgender patients in critical care need better-trained medical staff and specific guidelines.

Psoriasis rates in transgender people are similar to the general population, but hormone therapy might affect it.

Synthetic polypeptides in cosmetics may help with anti-aging, but their effectiveness on real skin is uncertain.

The healthcare for transgender veterans could be better with a more unified team approach.

Autoimmune-related phenomena do not affect the progression or characteristics of lichen sclerosus in women.

The transgender community in India has specific skin care needs and struggles to access dermatological services due to discrimination and financial issues.

A woman survived a massive lithium overdose that caused a form of hair loss.

Hormone therapy greatly improves the quality of life for adults seeking gender reaffirmation, but more research is needed in India.

Hormone therapy in transgender individuals can increase acne and affect hair growth and loss.

Topical 3% minoxidil effectively and safely enhances facial hair in transgender men.

Transgender women have similar fitness to cisgender women, while transgender men have higher fat and lower strength than cisgender men; hormone therapy affects body composition and strength.

Transgender individuals face unique skin issues, often due to hormone therapy, requiring specialized and stigma-free dermatologic care.

Facial hair is crucial for gender affirmation, but many face financial barriers to achieving desired results.

Alopecia in transgender individuals on hormone therapy can worsen emotional distress and affect self-esteem.

The guideline emphasizes a multidisciplinary approach and informed consent for gender-affirming hormone treatment, with regular follow-ups and individualized care.