research Author response: Hair follicle epidermal stem cells define a niche for tactile sensation
Skin stem cells in hair follicles are important for touch sensation.
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60-90 / 1000+ results research The cellular basis of mechanosensory Merkel-cell innervation during development
BMP signaling is essential for the development of touch domes.
research Club-like receptors respond to light touch but not to whisking
Club-like receptors detect light touch but not whisking.
research The sensory innervation of primate facial skin. II. Vermilion border and mucosa of lip
Monkey lips have dense sensory nerves similar to those in other skin areas, explaining their sensitivity.
research 559 Visualization of sweat suppression following botulinum toxin A by soluble microneedle arrays
Microneedle arrays deliver botulinum toxin effectively for sweat suppression, similar to injections.
research Three-Dimensional Morphology of Touch Domes in Human Hairy Skin by Correlative Light and Scanning Electron Microscopy
Touch domes in human skin are complex sensory structures not directly linked to hair.
research The existence of a linear system consisting of sympathetic endings in rat skin
Rat skin has a linear system of nerve fibers linked to hair follicles and muscles.
research Overexpression of neurotrophin 4 in skin enhances myelinated sensory endings but does not influence sensory neuron number
Increasing neurotrophin 4 in skin boosts nerve endings but not sensory neuron count.
research Role of BK channels and Kv4.2 channels in the electrophysiological properties of Merkel cells in rat whisker hair follicles
BK and Kv4.2 channels help Merkel cells in rat whiskers sense touch.
research A subpopulation of itch‐sensing neurons marked by Ret and somatostatin expression
Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.
research Potassium channel conductance as a control mechanism in hair follicles
research Lysophosphatidic acid and signaling in sensory neurons
Lysophosphatidic acid affects sensory neurons and may cause neuropathic pain and itch.
research 689 Regional differences in scalp innervation: A pilot study of the healthy scalp
The back of the scalp has more nerve fibers than the front, which may explain why some people feel more sensitivity there.
research Receptor types in cat hairy skin supplied by myelinated fibers.
Cats' hairy skin has different touch receptors connected by myelinated fibers.
research Peripheral patterns of calcitonin‐gene‐related peptide general somatic sensory innervation: Cutaneous and deep terminations
CGRP-IR axons may help maintain and renew tissues.
research Three-dimensional microanatomy of longitudinal lanceolate endings in rat vibrissae
Rat vibrissae have sensory terminals with specific structures that help detect hair movements.
research KCNQ4 K+ channels tune mechanoreceptors for normal touch sensation in mouse and man
research Distribution of P2X3‐immunoreactive fibers in hairy and glabrous skin of the rat
P2X3-IR fibers are widespread in rat skin and likely help detect pain.
research Delta Opioid Receptors Presynaptically Regulate Cutaneous Mechanosensory Neuron Input to the Spinal Cord Dorsal Horn
Delta opioid receptors help regulate touch sensation by reducing neurotransmitter release in the spinal cord.
research Innervation Patterns of Harp Seal (Pagophilus groenlandicus) Vibrissal Sensory Systems
Harp seals have different innervation patterns in their whiskers, with lateral whiskers having more axons than medial ones.
research Hair-follicle-associated pluripotent (HAP) stem cells
HAP stem cells can repair nerves and spinal cords by becoming Schwann cells.
research Neuronal plasticity of the “brain–skin connection”: stress-triggered up-regulation of neuropeptides in dorsal root ganglia and skin via nerve growth factor-dependent pathways
Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.
research Synaptic Long-Term Potentiation and Depression in the Rat Medial Vestibular Nuclei Depend on Neural Activation of Estrogenic and Androgenic Signals
Estrogen and androgen signals control synaptic changes in rat brains.
research A Study of the Expression of Small Conductance Calcium-Activated Potassium Channels (SK1-3) in Sensory Endings of Muscle Spindles and Lanceolate Endings of Hair Follicles in the Rat
SK2 channels help control sensory signals in rat muscle spindles and hair follicles.
research Early inductive events in ectodermal appendage morphogenesis
Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.
research Effects of botulinum toxin type A on histamine-induced itch and vasomotor responses in human skin
Botulinum toxin type A reduces itch and inflammation from histamine and may help treat certain skin conditions and hair loss.
research Radially patterned morphogenesis of murine hair follicle placodes ensures robust epithelial budding
research Spider joint hair sensilla: adaptation to proprioreceptive stimulation
Spider joint hair sensilla are adapted to sense movement during walking.
research Epidermal Growth Factor Receptor Regulates Skin Nerve Outgrowth and Branching
EGFR is essential for organized skin nerve growth and branching.
research 50285 Oxytocin receptor is present in keratinocytes near touch and pain sensory neurons
Oxytocin receptors are found in skin cells near touch and pain neurons.