April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The back of the scalp has more nerve fibers than the front, which may explain why some people feel more sensitivity there.
189 citations
,
May 1999 in “Microscopy Research and Technique” Neurotrophins, especially NGF, are crucial for pain development and management.
5 citations
,
November 2015 in “Journal of Cosmetic Dermatology” Effective pain relief methods for photoepilation include topical anesthetics, cooling devices, and skin stimulation.
October 2025 in “Journal of Neurophysiology” BK and Kv4.2 channels help Merkel cells in rat whiskers sense touch.
January 2022 in “Stem cell biology and regenerative medicine” Lymphatic vessels help hair follicles regenerate by interacting with stem cells.
10 citations
,
September 2024 in “Neural Regeneration Research” Stem cells improve nerve repair by enhancing blood vessel growth.
307 citations
,
November 1968 in “Journal of neurophysiology” Cats' hairy skin has different touch receptors connected by myelinated fibers.
June 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Dopaminergic neurons in the gut have distinct subtypes, some releasing both dopamine and acetylcholine.
11 citations
,
August 2006 in “Cell Biology International” Endothelin-1 helps amelanotic melanocytes stick and move better on certain proteins.
5 citations
,
June 2024 in “Developmental Cell” Activating TRPV1 can boost hair growth by involving neurons, macrophages, and fibroblasts.
19 citations
,
November 2014 in “Journal of Comparative Physiology A” Spider joint hair sensilla are adapted to sense movement during walking.
September 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Special gut cells help stem cells move to and fix injured areas by activating a specific signaling pathway.
12 citations
,
March 2022 in “Development” Mechanical forces are crucial in shaping our sensory organs during development.
July 2022 in “Biomedicines” 4-Aminopyridine improves skin wound healing and tissue regeneration by increasing cell growth and promoting nerve repair.
December 2022 in “Stem Cells and Development” Exosomes from stem cells help improve nerve repair in rats.
September 2004 in “Experimental Dermatology” The model effectively studies how sensory nerves interact with skin components, aiding research on wound healing and hair growth.
47 citations
,
August 2012 in “Cell Cycle” Stem cells in hair follicles can become neurons and other cells, especially in the upper part, useful for nerve repair.
April 2019 in “International research journal of pharmacy” Adiantum capillus extract reduces pain and swelling in animals.
160 citations
,
January 2014 in “Seminars in cell & developmental biology” Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.
November 2023 in “Baylor University Medical Center Proceedings” 2 citations
,
April 2014 in “PubMed” Epidermal neural crest stem cells from hair follicles can help repair nerve injuries.
47 citations
,
April 2001 in “Journal of Dermatological Science” IGF-I and HGF attract and stimulate hair follicle cells to move.
35 citations
,
January 2000 in “Journal of comparative neurology” Rat vibrissae have sensory terminals with specific structures that help detect hair movements.
February 2009 in “Journal of Investigative Dermatology” EGFR is essential for organized skin nerve growth and branching.
16 citations
,
November 2018 in “The journal of pain/Journal of pain” 14,15-EET may help reduce poststroke pain by affecting certain brain proteins.
109 citations
,
November 2011 in “Nature Neuroscience” 70 citations
,
February 2016 in “EMBO reports” Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.
50 citations
,
April 2021 in “Frontiers in Immunology” New therapies targeting skin neuroimmune interactions could treat neuropathic pain.
36 citations
,
September 2009 in “Molecular Neurobiology” 34 citations
,
July 2006 in “The Journal of Comparative Neurology” Increasing neurotrophin 4 in skin boosts nerve endings but not sensory neuron count.