59 citations
,
May 2014 in “Expert Opinion on Therapeutic Targets” The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
58 citations
,
January 2015 in “International Journal of Trichology” Platelet-rich plasma, which carries growth factors, could be a promising treatment for non-scarring hair loss, promoting hair growth and density with no major side effects.
58 citations
,
January 2006 in “Skin Pharmacology and Physiology” High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.
58 citations
,
September 1991 in “British Journal of Dermatology” Women with AGA often face anxiety, depression, and low self-esteem; psychological support is important.
57 citations
,
October 2018 in “Journal of The American Academy of Dermatology” Platelet-rich plasma treatment can significantly increase hair count and density in men with pattern baldness, and these improvements can last up to 3 months.
57 citations
,
July 2016 in “The Journal of Sexual Medicine” 5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.
57 citations
,
May 2016 in “Journal of Dermatological Treatment” PRP therapy may effectively treat hair loss, but more research needed.
57 citations
,
February 2014 in “Experimental Dermatology” Prostaglandin D₂ might be targeted for new male pattern baldness treatments.
56 citations
,
January 2019 in “Skin appendage disorders” The most common hair loss type at specialist clinics is androgenetic alopecia, especially in younger men, followed by alopecia areata and telogen effluvium, with differences seen across regions.
56 citations
,
June 2001 in “European journal of cardiovascular prevention & rehabilitation” Early balding linked to higher heart disease risk.
55 citations
,
July 2016 in “Dermatologic Therapy” Multiple treatments work best for hair loss.
55 citations
,
June 2006 in “Central European Journal of Public Health” Hair loss in older men is linked to higher rates of diabetes and high blood pressure.
54 citations
,
May 2018 in “Journal of The European Academy of Dermatology and Venereology” Low level laser therapy works best for hair loss, followed by PRP, finasteride, and minoxidil.
54 citations
,
July 2002 in “Clinical and Experimental Dermatology” DHT, a testosterone byproduct, causes male pattern baldness.
53 citations
,
June 2017 in “Skin appendage disorders” PRP treatment helps hair growth in most cases, but more research needed.
53 citations
,
March 2014 in “Cold Spring Harbor Perspectives in Medicine” The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.
53 citations
,
March 2010 in “British Journal of Dermatology” Alopecia common in teens, may indicate endocrine issue, minoxidil effective treatment.
52 citations
,
March 2010 in “British Journal of Dermatology” Alopecia areata shows a unique type 1 interferon signature, suggesting potential treatment by targeting this pathway.
52 citations
,
June 2009 in “Current Opinion in Endocrinology, Diabetes and Obesity” The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.
52 citations
,
April 2004 in “Journal of The American Academy of Dermatology” Male pattern baldness involves three mechanisms and finasteride can help reverse it.
51 citations
,
October 2012 in “International Journal of Immunopathology and Pharmacology” Finasteride works better than Serenoa repens for male hair loss.
51 citations
,
January 2012 in “Annals of Dermatology” Asian hair loss differs from Europeans; consider individual needs and psychological well-being for treatment.
51 citations
,
November 2011 in “British Journal of Dermatology” A gene called HDAC9 might be a new factor in male-pattern baldness.
50 citations
,
December 2008 in “Clinical Endocrinology” Hair loss in young men linked to higher risk of insulin resistance and metabolic issues.
49 citations
,
May 2013 in “JAMA Dermatology” Hair loss links to higher death risk from diabetes and heart disease; not a direct cause, but a marker for risk factors.
49 citations
,
January 2004 in “Dermatology” Men with a family history of hair loss are more likely to experience it themselves, especially if both parents have hair loss.
49 citations
,
June 2003 in “European journal of cardiovascular prevention & rehabilitation” Hair loss in middle-aged women is often linked to insulin resistance and a family history of hair loss, particularly from their fathers.
48 citations
,
February 2014 in “Fertility and Sterility” Women with PCOS often have hair loss, which is linked to acne or excess body hair but not to worse hormone or metabolic issues.
48 citations
,
April 2013 in “Expert Opinion on Investigational Drugs” Possible new treatments for common hair loss include drugs, stem cells, and improved transplants.
47 citations
,
December 2020 in “Journal of the European Academy of Dermatology and Venereology” The document concludes that understanding and treating hair loss requires recognizing its various types and using appropriate diagnostic tools and treatments.