68 citations
,
April 2002 in “Journal of Alternative and Complementary Medicine” Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.
58 citations
,
January 2006 in “Skin Pharmacology and Physiology” High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.
55 citations
,
June 2006 in “Central European Journal of Public Health” Hair loss in older men is linked to higher rates of diabetes and high blood pressure.
51 citations
,
December 2011 in “The Journal of Dermatology” New treatments for severe hair loss often fail, but some patients see hair regrowth with specific therapies, and treatment should be tailored to the individual's situation.
50 citations
,
March 2001 in “Clinics in Dermatology” Genes and hormones cause hair loss, with four genes contributing equally.
37 citations
,
January 2010 in “International Journal of Trichology” Hair loss affects quality of life, self-esteem, and confidence, but younger patients cope better.
35 citations
,
October 2006 in “Journal of Dermatology” Teen hair loss common in boys, linked to family history and mild symptoms.
30 citations
,
November 2013 in “PLOS ONE” Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.
28 citations
,
July 2017 in “Journal of Endocrinological Investigation” Early onset baldness in men may indicate a condition similar to PCOS, linked to heart disease, diabetes, and prostate issues.
26 citations
,
June 2016 in “Pediatric Dermatology” Premature hair graying in young Turkish adults is more likely if they have stress, a family history of graying, drink alcohol, have chronic diseases, are older, or are taller.
26 citations
,
January 2013 in “BMJ Open” Severe baldness on the top of the head is linked to a higher chance of heart disease, especially in men under 60.
25 citations
,
November 2008 in “Facial Plastic Surgery” Dr. Michael Beehner recommends a personalized, careful approach to hairline design in hair replacement surgery for a natural look.
24 citations
,
March 2017 in “Journal of The European Academy of Dermatology and Venereology” Finasteride use linked to increased risk of sexual dysfunction, especially in younger people.
24 citations
,
October 1994 in “Fertility and Sterility” People with hair loss may have different levels of certain hormones due to changes in hormone processing.
23 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” FPHL causes hair loss in women due to genetics and hormones; minoxidil and anti-androgens are treatments, and early intervention is advised.
20 citations
,
August 2016 in “International Journal of Cancer” Men with male pattern baldness have a higher risk of certain skin cancers, especially on the scalp.
19 citations
,
May 2020 in “Cells” Substance from human umbilical cord blood cells promotes hair growth.
19 citations
,
October 2017 in “The FASEB Journal” Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.
18 citations
,
January 2013 in “Annals of Dermatology” AGA increased yearly, type I most common, and family history and seborrheic dermatitis often linked.
17 citations
,
October 2003 in “Brazilian Journal of Medical and Biological Research” The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.
12 citations
,
March 2019 in “Lasers in Surgery and Medicine” Low-level laser therapy improves hair growth and dermal papilla cell function.
8 citations
,
June 2020 in “Dermatologic Therapy” Hair loss lowers quality of life, causing embarrassment, frustration, and sexual rejection.
7 citations
,
August 2021 in “Journal of the European Academy of Dermatology and Venereology” Early treatment of fibrosing alopecia in a pattern distribution may improve outcomes.
7 citations
,
January 2012 Neural networks can effectively predict hair loss.
6 citations
,
January 2021 in “International Journal of Molecular Sciences” Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.
5 citations
,
April 2018 in “Journal of Cosmetic Dermatology” New 5% minoxidil formula safely and effectively treats male hair loss.
3 citations
,
October 2019 in “Dermatologic Therapy” Hair loss in men is mainly caused by hormones and genes, and while current treatments can slow it down, they can't fully stop it.
3 citations
,
January 2018 in “İstanbul Kuzey Klinikleri” Hair loss was found in 37.4% of surveyed rural high-school students in Eskisehir, Turkey, affecting their quality of life, especially in general health and mental well-being.
3 citations
,
October 1988 in “Clinics in Dermatology” Using 3% topical minoxidil can help women with hair loss, but more research is needed.
1 citations
,
January 2017 in “Journal of Community & Public Health Nursing” Wearing a cap doesn't affect quality of life for Indian men with hair loss, but severe hair loss does lower it. Older men have more severe hair loss, and those who wear caps more often want less treatment.