November 2025 in “Journal of Pharmacy and Pharmacology” PEDF reduces oxidative damage and supports stem cells.
December 2024 in “American Journal of Biomedical Science & Research” Stem cell therapy shows promise for regenerating tissues and treating diseases, especially in older people.
28 citations
,
September 2013 in “Biogerontology” October 2022 in “European Heart Journal” Potent extracellular vesicles from cardiosphere-derived cells can improve heart health and other functions in aging.
3 citations
,
March 2023 in “Life” Obesity can worsen wound healing by negatively affecting the function of stem cells in fat tissue.
66 citations
,
July 2015 in “Journal of Molecular Biology” The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.
13 citations
,
September 2017 in “Oncotarget” A certain signaling pathway in mice, when increased, causes hair to gray by depleting the cells that give hair its color.
11 citations
,
March 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” Old hair follicles grew better when moved to a young environment.
5 citations
,
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Aging skin shows thinner layers, fewer hair follicles, and new biomarkers like increased space between cells and smaller sebaceous glands.
1 citations
,
April 2016 in “CRC Press eBooks” Skin aging reflects overall body aging and can indicate internal health conditions.
75 citations
,
March 2014 in “Journal of Investigative Dermatology” Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.
38 citations
,
February 2021 in “Journal of Investigative Dermatology” Aging slows wound healing due to weaker cells and immune response.
July 2023 in “British journal of dermatology/British journal of dermatology, Supplement” Aging changes scalp cells, possibly affecting hair health in older women.
333 citations
,
February 2010 in “Cell Stem Cell” Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.
211 citations
,
November 2018 in “Nature Cell Biology” Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.
59 citations
,
February 2012 in “Journal of Dermatological Science” Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.
20 citations
,
July 2010 in “Skin Research and Technology” Aging makes hair thinner and rougher, with less clear edges.
13 citations
,
March 2018 in “Journal of Sociology” The anti-ageing treatment market is growing by exploiting fears of ageing with unproven promises, which could harm public trust and genuine science.
12 citations
,
December 2021 in “Aging” A new painless method to collect hair follicles helps study DNA damage and aging.
11 citations
,
June 2016 in “npj Regenerative Medicine” The symposium concluded that understanding how different species repair tissue and how this changes with age can help advance regenerative medicine.
7 citations
,
June 2021 in “Cell Proliferation” Low oxygen levels improve the function of hair and skin cells when they are in direct contact.
1 citations
,
January 2019 in “Advances in stem cells and their niches” Epidermal stem cells are crucial for skin health and problems with them can cause issues like poor wound healing, cancer, and aging.
Different types of skin cells and immune cells play a role in healing UV-damaged skin, with chronic UV exposure causing lasting damage to certain skin cells.
March 2025 in “Aging Cell” Reducing IGF-1 can help rejuvenate hair follicles and prevent hair graying and loss.
January 2025 in “Health engineering.” Combining stem cells and organoids could improve skin regeneration treatments.
January 2017 in “Chemistry & Industry” Eating fewer calories may slow aging and removing old cells can increase lifespan in mice.
127 citations
,
November 2010 in “Pigment cell & melanoma research” We need more research on human hair follicle pigmentation, not just mouse models.
January 2023 in “Dermatology” Ageing and increased senescent cells significantly contribute to common hair loss.
1 citations
,
January 2025 in “Aging and Disease” Lengthening telomeres may reverse aging and extend lifespan.
April 2025 in “Cosmetics” RCDP NCs are promising anti-aging cosmetic ingredients that improve skin health by reducing oxidative stress and enhancing cell function.