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Inhibiting mTORC2 can reduce DNA repair and increase cancer cell death, suggesting potential for targeted brain cancer treatments.

A rare genetic mutation found in an Indian family can be detected through prenatal screening.

Ptch2 plays a key role in controlling stem cell function and the ability to regenerate after birth.

The patient's hair was thinner and had fewer lipids due to a genetic mutation.

Skin lesions in Carney Complex are caused by a gene change in some skin cells that leads to increased pigmentation and may lead to tumors.

A Gsdma3 mutation causes hair loss due to stem cell damage from skin inflammation.

Two specific SNPs in the TRPS1 gene cause excessive hair growth by altering the protein's structure.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Kir6.1 mutations in Cantú syndrome increase channel sensitivity and hyperpolarization, while SUR2B mutations do not.

Agouti and AGRP affect pigmentation and obesity, with implications for metabolic disorders.

AP-1 and TGFß work together to drive resistance in basal cell carcinoma, suggesting new treatment options.

GLI2 increases follistatin production in human skin cells.

5α-reduced neurosteroids may help regulate glial cell differentiation.

A girl had rickets due to a gene mutation affecting vitamin D response.

Patients with certain FoxN1 gene mutations have severe immune issues but normal skin and hair.

Mutations in the RBPJ gene cause Adams-Oliver Syndrome.

Tsc2-deficient stem cells can help understand and treat TSC-related tumors.

Keratinocyte growth factor significantly alters skin and tissue development.

A new genetic mutation in the hairless gene causes a rare hair loss disorder.

PCR genotyping in cre-loxP mice can be inaccurate due to unintended gene deletions in non-target tissues.

The mutated hairless gene causes hair loss by acting as a new type of corepressor affecting thyroid hormone receptors.

Certain proteins and their receptors are more active during the growth phase of human hair and could be targeted to treat hair disorders.

Higher PHGDH levels cause unusual melanin buildup in hair follicles.

A rare genetic mutation causes resistance to vitamin D, leading to severe rickets and requiring high doses of calcium and vitamin D for treatment.

A specific mutation known for causing cancer is also found to cause a skin condition in a young girl.

HR protein causes abnormal hair cycles by increasing Tgf-β2 and reducing miR-31.

AXR3 and SHY2 genes control the growth and timing of root hair development in plants.

LPR1 regulates root growth under low phosphate stress independently of SIZ1 in Arabidopsis thaliana.

Mutant Cx43 causes slower wound healing and hair growth issues in ODDD.

Hair follicles in the back of the rosette fancy mouse have reversed orientations due to a gene mutation.