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Overexpressing the glucocorticoid receptor in mice leads to abnormal skin development and reduced inflammation.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Mutant MK6a transgenes in mice cause blistering, hair loss, and potential human alopecia.

Overexpressing 14-3-3σ in mice skin reduces cell growth and hair density.

The mutant HR bmh protein mis-localizes in cells, affecting skin and hair development.

Researchers found an RNA transcript that might help control a growth factor linked to tumor development.

A specific mutation in the TRPV3 gene causes hair follicle cells to develop improperly, leading to hair loss.

RAR-gamma 1 is important for normal skin maintenance and differentiation.

TRPS1 is crucial for bone, kidney, and hair follicle development.

A gene mutation in mice causes skin defects and early death.

LGD1069 effectively prevents breast tumors in mice without toxicity.

RXRα is crucial for hair growth and skin cell function.

Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.

Disrupting Acvr1b in mice causes severe hair loss and thicker skin.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

High levels of ODC and a mutant Ha-ras gene cause tumors in mice.

A new genetic mutation in mice causes permanent hair loss and skin wrinkling.

A new mutation in the TRPS1 gene was found in a Ukrainian girl with Trichorhinophalangeal syndrome type I.

Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.

Blocking mTORC1 reduces skin tumor growth in mice.

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

Progerin affects cell shape but not hair or skin in mice.

Mutant stem cells adapt their metabolism differently to outcompete normal cells in the skin.

High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.

GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.

A rare EGFR mutation in newborns leads to severe health issues and early death.

AGD1's PH domain is essential for its role in root hair growth and polarity.

Using special RNA to target a mutant gene fixed hair problems in mice.