research Mimicking fat grafting of fibrotic scars using 3D‐organotypic skin cultures
Fat grafting reduces scar fibrosis but may slow skin healing.
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research Epidermal homeostasis: a balancing act of stem cells in the skin
Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.
research The Hair Follicle
Dogs could be good models for studying human hair growth and hair loss.
research Assessment of markers expressed in human hair follicles according to different skin regions
Different body parts have varying levels of certain hair follicle markers.
research Understanding the functional contribution of dermal stem cells to hair follicle regeneration and skin wound healing
Dermal stem cells help regenerate hair follicles and heal skin wounds.
research DNA Methylation as an Epigenetic Memory Keeper during Skin Development and Regeneration
DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.
research Temporary hair removal by low fluence photoepilation: Histological study on biopsies and cultured human hair follicles
Low fluence photoepilation temporarily removes hair by targeting the hair follicle's pigmented area without severe damage.
research Resting no more: re‐defining telogen, the maintenance stage of the hair growth cycle
The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.
research The Thyroid Hormone Analogue KB2115 (Eprotirome) Prolongs Human Hair Growth (Anagen) Ex Vivo
KB2115 (eprotirome) can safely extend the hair growth phase without damaging cells or changing hair color.
research Advanced Medical Therapies in the Management of Non-Scarring Alopecia: Areata and Androgenic Alopecia
Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.
research Comparing the delivery to the hair bulb of two fluorescent molecules of distinct hydrophilicities by different nanoparticles and a serum formulation
Serum formulations were better at delivering molecules to the hair bulb than nanoparticles.
research Enhanced restoration ofin situ-damaged hairs by intradermal transplantation of trichogenous dermal cells
Transplanting a mix of specific skin cells can significantly improve the repair of damaged hair follicles.
research Fundamentals
Finasteride and minoxidil are effective, low-risk treatments for male hair loss, and patient education on these therapies is important.
research Molecular principles of hair follicle induction and morphogenesis
Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.
research Indications for a brain‐hair follicle axis: inhibition of keratinocyte proliferation and up‐regulation of keratinocyte apoptosis in telogen hair follicles by stress and substance P
Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.
research Activin Controls Skin Morphogenesis and Wound Repair Predominantly via Stromal Cells and in a Concentration-Dependent Manner via Keratinocytes
Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.
research Drug discovery for alopecia: gone today, hair tomorrow
Topical drugs and near-infrared light therapy show potential for treating alopecia.
research The cycling hair follicle as an ideal systems biology research model
The hair follicle is a great model for research to improve hair growth treatments.
research Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: An update
The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
research PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis
PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.
research Hair Coloration by Gene Regulation: Fact or Fiction?
Gene regulation could revolutionize hair color by altering pigmentation from within.
research Growth and viability of Liaoning Cashmere goat hair follicles during the annual hair follicle cycle
Liaoning Cashmere goat hair follicles show synchronized growth patterns with lowest activity in May.
research TR3 is preferentially expressed by bulge epithelial stem cells in human hair follicles
TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.
research Molecular and spatial design of early skin development
The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.
research Characterisation of CD4+ stem cells of the skin and their role in skin homeostasis and tumourigenesis
CD4+ skin cells may be precursors to basal cell carcinoma.
research Stem Cells and their Niches
The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.
research Integrated Analysis of miRNAs and mRNA Profiling Reveals the Potential Role of miRNAs in Sheep Hair Follicle Development
Certain miRNAs may play a role in sheep hair follicle development, which could help improve wool production.
research Stress-induced chemokine production by hair follicles recruits dendritic cells to sites of minor trauma
Hair follicles help attract immune cells to minor skin injuries.
research Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of β-catenin in mice
Wnt signaling is vital for cell growth, development, and cancer research.
research Pioneer factors govern super-enhancer dynamics in stem cell plasticity and lineage choice
Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.