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Disruption of glycinergic circuits increases pain sensitivity, suggesting new pain treatment options.

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

Targeting neurosteroids may help prevent drug relapse.

PPARα agonists may help treat alopecia areata by reducing inflammation.

AH-001 could be a safer and more effective treatment for hair loss.

New compounds with carborane showed anti-androgen effects similar to flutamide.

Neurosteroids may help treat disorders with too much dopamine activity.

Antiandrogenic drugs could be a good treatment option for frontal fibrosing alopecia.

Agomelatine may help reduce benign prostatic hyperplasia by blocking certain inflammatory pathways.

A new topical treatment for hair loss shows strong hair growth effects with low toxicity.

Allopregnanolone may help prevent nicotine withdrawal symptoms.

Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.

GnRH agonists can help manage recurrent priapism in sickle cell patients, but long-term safety is unclear.

Using a certain drug on the skin can help prevent hair loss caused by pulling on the hair.

Neuroactive steroids affect cocaine's rewarding effects through the ς₁ receptor.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

New A-homo-B, 19-dinor steroids showed strong antiandrogenic activity without affecting the enzyme 5α-reductase or androgen receptor binding.

New compounds were made and tested, with compound 6 showing potential for treating prostate-related diseases.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Some drugs can cause serious side effects like heart issues and nervous system problems, but certain drugs for Parkinson's and overactive bladder may be safer, though they still have some common side effects.

OXTR agonists may promote hair growth and be effective for treating hair loss.

New compounds were made that are promising for prostate cancer therapy.

PEA reduces pain by increasing neurosteroid synthesis in the spinal cord.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Aromoline and DRD4 are potential targets for osteoarthritis treatment.

Using GnRHa agonists helps diagnose and treat ovarian hyperthecosis when surgery isn't possible.

Using existing drugs for new purposes could be a cost-effective way to treat chest pain and non-clogged heart arteries, with some drugs for lung blood pressure showing promise but needing more testing.

The steroids allopregnanolone and allotetrahydrodeoxycorticosteron worsened absence seizures in rats.