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Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

Alstonia boonei phytochemicals show promise as alternative treatments for BPH with fewer side effects than current drugs.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

14,15-EET may help reduce poststroke pain by affecting certain brain proteins.

Nanocarriers like liposomes and cyclodextrins improve how angiotensin-(1-7) is delivered in the body.

Thyroid receptor β can help develop new drugs to treat hair loss.

Blocking α-toxin helps heal Staphylococcus aureus-infected wounds faster in both normal and diabetic mice, with different effects on their immune responses.

Third-generation antihistamines are the safest and most effective for allergies.

Mineralocorticoid receptor antagonist therapy does not significantly reduce mortality in COVID-19 patients.

Blocking certain proteins can reduce skin inflammation caused by cancer treatment.

Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.

Antibody drug conjugates show promise in targeting cancer cells while reducing harm to healthy cells.

Breast cancer treatments work better with AR activation, improving results and reducing side effects.

Alpha-blockers are the most effective and widely used treatment for lower urinary tract symptoms, with minimal side effects.

Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.

Certain amino acids in 5AR1 and 5AR2 are crucial for binding and resistance to Finasteride.

Setipiprant may reduce inflammation by blocking an enzyme called aldose reductase.

The new compound was more effective than finasteride in reducing markers of hair loss and prostate issues in cell tests.

Targeting the RAAS with small molecules can improve cardiovascular disease treatments.

TRPA1 and TRPV1 channels don't affect mechanotransduction in rat sinus hair follicles.

Dutasteride and finasteride affect different cell types differently.

Mutations at Val-889 and Arg-752 disrupt key interactions in androgen receptor dimerization.

Understanding WNT signaling proteins can help predict and treat certain types of hair loss.

Vasodilators may worsen abdominal aortic aneurysm.

New curcumin analogues help fight prostate cancer by breaking down androgen receptors.

Argireline significantly reduces wrinkles.

SARM-induced changes in the androgen receptor are specific to each ligand and affect stability and protein interactions.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

5-alpha reductase inhibitors slightly reduce urinary symptoms and may lower surgery and acute retention risks in men.