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Optimization of LC Method for the Determination of Testosterone and Epitestosterone in Urine Samples for Biomedical and Anti-Doping Research

research Optimization of LC method for the determination of testosterone and epitestosterone in urine samples in view of biomedical studies and anti-doping research studies

21 citations , November 2010 in “Talanta”

Researchers developed a reliable method to measure testosterone and epitestosterone in urine for medical and anti-doping use.

Synthesis and Structure–Activity Studies of Side-Chain Derivatized Arylhydantoins for Investigation as Androgen Receptor Radioligands

research Synthesis and structure–activity studies of side-chain derivatized arylhydantoins for investigation as androgen receptor radioligands

18 citations , April 2001 in “Bioorganic & Medicinal Chemistry Letters”

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

Taking Advantage of Phenotype Variability in a Local Animal Genetic Resource: Identification of Genomic Regions Associated with the Hairless Phenotype in Casertana Pigs

research Taking advantage from phenotype variability in a local animal genetic resource: identification of genomic regions associated with the hairless phenotype in Casertana pigs

16 citations , April 2018 in “Animal Genetics”

Researchers found two genes that may explain why some Casertana pigs don't have hair.

research Advanced Medical Therapies in the Management of Non-Scarring Alopecia: Areata and Androgenic Alopecia

14 citations , November 2020 in “International Journal of Molecular Sciences”

Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.

research Extracellular fraction of adipose tissue as an innovative regenerative approach for vitiligo treatment

14 citations , May 2019 in “Experimental Dermatology”

Fat tissue extract may help treat vitiligo by reducing cell stress and promoting skin repair.

research Mechanisms of tolerance and potential therapeutic interventions in Alopecia Areata

12 citations , May 2017 in “Pharmacology & therapeutics”

Targeting immune tolerance issues in Alopecia Areata could restore hair growth and maintain remission.

research Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases

11 citations , February 2016 in “Current Medicinal Chemistry”

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Association of Gly972Arg Variant of Insulin Receptor Substrate-1 and Gly1057Asp Variant of Insulin Receptor Substrate-2 with Polycystic Ovary Syndrome in the Chinese Population

research Association of Gly972Arg variant of insulin receptor subtrate-1 and Gly1057Asp variant of insulin receptor subtrate-2 with polycystic ovary syndrome in the Chinese population

10 citations , October 2014 in “Journal of Ovarian Research”

The IRS-2 Asp/Asp genotype may increase the risk of PCOS in Chinese women, especially if they are not obese.

research The E6/E7 oncogenes of human papilloma virus and estradiol regulate hedgehog signaling activity in a murine model of cervical cancer

9 citations , May 2019 in “Experimental Cell Research”

HPV genes and estradiol increase a cancer-related signaling pathway, which may be targeted for cervical cancer treatment.

research Hyperandrogénie féminine

9 citations , November 2013 in “Presse Medicale”

The document concludes that managing female hyperandrogenism requires a combination of identifying the cause, lifestyle changes, medication, and cosmetic treatments.

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