January 2015 in “Springer eBooks” Chronic kidney disease can cause hair loss, which may be related to zinc deficiency or certain medications, and sometimes hair grows back when the underlying issue is treated.
January 2015 in “International Journal of Research in Medical Sciences” A patient with HAIR-AN syndrome, PCOS, and Hashimoto's thyroiditis improved with early diagnosis and treatment to prevent serious health problems.
April 2011 in “Global journal of health science” Aldactone effectively reduces hair thickness in women with excessive hair growth, both alone and with other treatments.
April 2011 in “Global journal of health science” Spironolactone effectively makes hair shafts thinner in women with excessive hair growth.
June 2003 in “Obstetrical & Gynecological Survey” Hair loss in women can be treated with hormone therapy.
September 1997 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Blocking IL-1 could help treat some hair loss conditions; alopecia affects liver detox systems; spironolactone is better than finasteride for female hair growth; focusing on the catagen hair phase could lead to new alopecia treatments.
September 1997 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Spironolactone is more effective than finasteride in treating excessive hair growth in women.
Treatment improved symptoms in a woman with HAIR-AN syndrome.
January 1994 in “Journal of Dermatological Treatment” Spironolactone helped reduce excessive facial hair in a woman with porphyria cutanea tarda.
Spironolactone was effective in reducing hair growth in women with hirsutism.
January 1987 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Norethisterone (jenapharm) therapy is effective for endometrial cancer.
April 2023 in “Journal of Investigative Dermatology” Low-dose spironolactone effectively treats female pattern hair loss with mild side effects.
September 2022 in “Journal of The American Academy of Dermatology” Dermatologists should monitor potassium levels in women taking spironolactone for acne, hair loss, and hirsutism.
March 2022 in “International journal of pharmaceutical sciences review and research” PCOS is a hormonal issue in women that is usually treated with birth control pills, metformin, and lifestyle changes, with early treatment helping to reduce complications and improve life quality.
February 2022 in “Chinese Journal of Dermatology” A 36-year-old woman with worsening hair loss over 10 years was treated with various medications, and after six months, her hair loss did not worsen significantly.
November 2021 in “Elsevier eBooks” Antiandrogens are used to manage polycystic ovary syndrome by reducing androgen levels or controlling their effects, often combined with lifestyle changes and other treatments.
February 2024 in “Practical Diabetes” Spironolactone helps reduce hospital visits and death from heart issues, lowers blood pressure, but has unclear effects on heart failure with normal heart pump function and can cause high potassium and breast enlargement in men.
July 2025 in “Journal of Investigative Dermatology” Spironolactone can safely lower blood pressure in patients on other blood pressure medications, but may slightly increase the risk of low blood pressure.
Spironolactone is effective and safe for treating acne.
Spironolactone effectively treats hormonal acne, hair loss, and excess hair growth in women.
135 citations
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March 1984 in “Fertility and sterility” Higher levels of unbound testosterone are linked to increased insulin resistance, especially in women with polycystic ovary syndrome.
19 citations
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July 1990 in “Cleveland Clinic journal of medicine” Androgen excess disorders in women were effectively treated with spironolactone, estrogen, and dexamethasone.
October 2015 in “Elsevier eBooks” Spironolactone can cause side effects like high potassium levels and breast enlargement, and patients need careful monitoring.
May 2024 in “Reactions weekly”
28 citations
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July 2022 in “Endocrine” Low prolactin in young women may increase heart and metabolism risks.
March 2019 in “Reactions Weekly”
195 citations
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May 2003 in “Obstetrics and gynecology (New York. 1953. Online)/Obstetrics and gynecology” Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.
165 citations
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February 1994 in “Fertility and Sterility” Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.
151 citations
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May 2014 in “American Journal of Clinical Dermatology” Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.
149 citations
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July 2002 in “Dermatologic clinics” Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.