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This enzyme helps metabolize fatty acids and isoleucine, and could be key in treating neurological diseases and certain cancers.

The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Finasteride effectively inhibits the enzyme steroid 5 alpha-reductase II.

Some dibenzo compounds might help treat cancer with fewer side effects.

5α-reductases increase epitestosterone's effect on androgen receptors.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

5α-reductase affects dopamine receptors linked to sensorimotor gating, which may help understand disorders like schizophrenia.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

The enzyme Dgat1 is essential for healthy hair and skin by controlling retinoid levels.

Certain derivatives are more effective 5α-reductase type 2 inhibitors than finasteride.

Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

5α-reductase 2 is crucial for stress response in male rats.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

The compound 4c effectively inhibits the enzyme linked to hair loss.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

The compounds tested could potentially treat hair loss and alopecia.

Glucocorticoids reduce fat production in liver cells, while androgens increase it in females; manipulating certain enzymes can influence these effects.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

The study found that the enzyme linked to acne is present in the same areas of both acne-affected and normal skin.

DK peptides can reduce hair loss by inhibiting the 5α-reductase enzyme and have antioxidant effects.

The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.

Removing REDD1 in mice increases skin fat by making fat cells larger and more numerous.

New compounds show promise for treating benign prostate hyperplasia with fewer side effects.

A brominated phenoxy compound effectively inhibits a human enzyme and shows potential for clinical use.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

Gene variant linked to prostate cancer, hormone levels, and hair loss.