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Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

Enzyme activities do not cause early pubic hair in these girls.

Increased ODC expression makes normally tumor-resistant mice more prone to tumor development.

QSOX enzymes help form protein bonds in cells, especially in tissues with high secretory activity.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

Fermentation of Finasteride with Ocimum sanctum L. creates new metabolite that inhibits tyrosinase.

New compounds may help treat prostate cancer by reducing cell growth.

Finasteride's metabolites were identified, helping understand how the drug is processed in the body.

Certain drugs can reduce bladder muscle contractions, potentially helping treat bladder diseases.

Introducing the OTC gene improved symptoms in mice with OTC deficiency.

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.

Finasteride and dutasteride may cause depression and anxiety, especially in younger men.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Finasteride effectively blocks enzyme causing male pattern baldness.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

The method effectively measures drug impact on DHT levels in prostate treatments.

Inward rectifier potassium channels are important in many body functions and diseases, and could be potential drug targets.

Inhibiting ornithine decarboxylase may help prevent certain skin cancers.

XEDAR deficiency prevents muscle degeneration in EDA-A2 transgenic mice.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Finasteride may cause kidney damage.

The study identified a key protein involved in producing underarm odor and found ways to inhibit it.

Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, which could be a new target for treating hair loss and other skin conditions driven by testosterone.

Balancing lipophilicity and solubility is key for effective and safe ketorolac prodrugs.

The anti-hangover product may boost enzyme activity to help prevent brain damage.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Active oxygen scavengers can reverse the suppression of hair cell growth caused by androgens.