19 citations
,
May 1979 in “Archives of internal medicine” Minoxidil effectively lowers blood pressure and initially increases plasma renin activity without raising aldosterone levels.
56 citations
,
January 1999 in “The Analyst” The method accurately measures certain steroids in human hair, showing different levels in males and females.
38 citations
,
September 2021 in “Signal Transduction and Targeted Therapy” Genetic differences affect COVID-19 severity and treatment development.
1 citations
,
October 2022 Antioxidants might help manage Long Covid by addressing oxidative stress and nutrient imbalances.
1 citations
,
October 2022 The conclusion suggests that managing antioxidant levels and the calcium to magnesium ratio may help address Long Covid and related chronic fatigue conditions.
19 citations
,
January 1993 in “Dermatologic Clinics”
January 2022 in “Current Enzyme Inhibition” New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.
13 citations
,
November 2005 in “Epilepsia” Deoxycorticosterone and its metabolites help prevent seizures by interacting with specific receptors.
45 citations
,
April 2021 in “Current Treatment Options in Oncology” ADT for prostate cancer may harm the heart, but GnRH antagonists might be safer.
January 2019 in “Oncogen” Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.
July 2025 in “Journal of Investigative Dermatology” Spironolactone can safely lower blood pressure in patients on other blood pressure medications, but may slightly increase the risk of low blood pressure.
23 citations
,
July 1979 in “Canadian journal of biochemistry” Spironolactone reduces the number of androgen receptor sites in rat skin by blocking them with its metabolite.
Spironolactone effectively treats hormonal acne, hair loss, and excess hair growth in women.
5 citations
,
December 2022 in “Viruses” Antiandrogens may help prevent or treat COVID-19 by blocking virus entry into cells.
6 citations
,
January 2024 in “Cancers” Antiandrogens don't help with COVID-19 and aren't recommended.
19 citations
,
October 2019 in “Clinical and Experimental Dermatology” Spironolactone reduces pain and lesions in hidradenitis suppurativa patients.
3 citations
,
July 1990 in “Acta dermato-venereologica” A man's baldness improved possibly due to a medication that blocks male hormones.
20 citations
,
December 1997 in “Clinical Endocrinology” Spironolactone may help reduce hair loss in androgenic alopecia.
36 citations
,
July 2022 in “Journal of Medicinal Chemistry” Therapies targeting the androgen receptor are being developed to treat prostate cancer and improve bone and muscle health.
October 2019 in “European heart journal” Androgen-deprivation therapies increase the risk of certain heart conditions, but testosterone treatment may help.
May 2023 in “Reactions Weekly” January 2013 in “Reactions Weekly”
142 citations
,
March 2019 in “Frontiers in Cellular Neuroscience” The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” LX-38 is a safer drug option for treating prostate issues and hair loss without hormonal side effects.
52 citations
,
February 2006 in “Current pharmaceutical design” 5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” LX-38 is a safer drug option for hair loss and prostate issues without hormonal side effects.
February 2025 in “Journal of the American Academy of Dermatology” Spironolactone helps prevent swelling caused by minoxidil in women with hair loss.
May 2024 in “Reactions weekly”
49 citations
,
January 2021 in “Journal of The European Academy of Dermatology and Venereology” Anti-androgens, like finasteride, dutasteride, and spironolactone, may lessen the severity of COVID-19 in men, leading to fewer ICU admissions.
8 citations
,
May 2020 in “Arthritis research & therapy” DHT inhibition may increase spinal bone growth in ankylosing spondylitis.