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research Modulating Aging and Aging-related Symptoms Using Endogenous Small Molecules

January 2019

A molecule called α-ketobutyrate was found to extend lifespan and improve aging-related symptoms in worms and mice by activating certain cellular pathways and may help develop anti-aging treatments for humans.

research Decision letter: Plant Trans-Golgi Network/Early Endosome pH regulation requires Cation Chloride Cotransporter (CCC1)

September 2021

CCC1 is essential for ion balance and proper plant cell function.

research Synthesis, Crystal Structure and Supramolecular Features of Novel 2,4-Diaminopyrimidine Salts

5 citations , January 2024 in “Crystals”

The salts have diverse molecular packing with significant hydrogen interactions.

research Cisd2 deficiency impairs neutrophil function by regulating calcium homeostasis via Calnexin and SERCA

April 2024 in “BMB Reports”

Lack of Cisd2 disrupts calcium balance in cells, leading to poorly functioning neutrophils.

research ASCORBIC ACID 2-PHOSPHATE PROMOTES HAIR GROWTH

January 2007

Bilayer Dressing Based on Aerogel/Electrospun Mats With Self-Catalytic Hydrogen Sulfide Generation and Enhanced Antioxidant Ability

research Bilayer dressing based on aerogel/electrospun mats with self-catalytic hydrogen sulfide generation and enhanced antioxidant ability

6 citations , December 2022 in “Journal of Materials Chemistry B”

The dressing generates hydrogen sulfide to help heal wounds faster by reducing inflammation and promoting cell growth.

research c-Kit - The Novel Receptor: Physiological Roles, Downstream Signaling and Implications in Cancer

4 citations , January 2021 in “Journal of Clinical Medical Research”

c-Kit is important for heart regeneration and cancer development.

Scientific Opinion on the Substantiation of a Health Claim Related to KF2BL20 and Maintenance of Normal Hair Pursuant to Article 13(5) of Regulation (EC) No 1924/2006

research Scientific Opinion on the substantiation of a health claim related to KF2BL20 and maintenance of normal hair pursuant to Article 13(5) of Regulation (EC) No 1924/2006

1 citations , July 2012 in “EFSA journal”

KF2BL20 does not have proven benefits for maintaining normal hair.

A New Start: Investigating The Role Of The Transcription Factor PDF2 In Arabidopsis

research A new START

July 2024 in “New Phytologist”

PDF2 senses specific lipids and regulates root growth and gene expression in Arabidopsis.

research Strontium: A Potent and Selective Inhibitor of Sensory Irritation and Topical Anti-inflammatory

May 2003 in “Hair transplant forum international”

Strontium can effectively reduce skin irritation and inflammation.

research Protein Carbonylation as a Reliable Read-Out of Urban Pollution Damage/Protection of Hair Fibers

September 2022 in “Cosmetics”

A Study of the Expression of Small Conductance Calcium-Activated Potassium Channels (SK1-3) in Sensory Endings of Muscle Spindles and Lanceolate Endings of Hair Follicles in the Rat

research A Study of the Expression of Small Conductance Calcium-Activated Potassium Channels (SK1-3) in Sensory Endings of Muscle Spindles and Lanceolate Endings of Hair Follicles in the Rat

17 citations , September 2014 in “PLoS ONE”

SK2 channels help control sensory signals in rat muscle spindles and hair follicles.

research The JAK/STAT signaling pathway: from bench to clinic

489 citations , November 2021 in “Signal Transduction and Targeted Therapy”

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

research Loss of Msx2 Function Down-Regulates the FoxE3 Expression and Results in Anterior Segment Dysgenesis Resembling Peters Anomaly

22 citations , April 2012 in “The American journal of pathology”

Loss of Msx2 function causes eye development issues similar to Peters anomaly.

research Skin-type-dependent development of murine mechanosensory neurons

13 citations , August 2023 in “Developmental Cell”

Mechanosensory neurons adapt to different skin types after birth.

research RETRACTED ARTICLE: Up-regulated lncRNA5322 elevates MAPK1 to enhance proliferation of hair follicle stem cells as a ceRNA of microRNA-19b-3p

9 citations , June 2019 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)”

A specific RNA increases hair stem cell growth and skin healing by affecting a protein through interaction with a microRNA.

research Role of regeneration in tissue repairing and therapies

6 citations , January 2015 in “Journal of regenerative medicine & tissue engineering”

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

research Characterization of Growth Secondary Hair in Min Pig Activated by Follicle Stem Cell Stimulated by Wnt and BMP Signaling Pathway

1 citations , April 2023 in “Animals”

Wnt and BMP pathways stimulate hair growth in Min pigs, with Wnt being more effective.

research Bioconversion, Pharmacokinetics, and Therapeutic Mechanisms of Ginsenoside Compound K and Its Analogues for Treating Metabolic Diseases

1 citations , February 2024 in “Preprints.org”

Ginsenoside compound K shows promise for treating metabolic diseases like obesity and diabetes, but more research is needed on its safety and effectiveness.

$Synthesis and Structural Characterization of a New Dinuclear Platinum(III) Complex, [Pt2Cl4(NH3)2{μ-HN=C(O)Bu^t}2]$

research Synthesis and structural characterization of a new dinuclear platinum(III) complex, [Pt₂Cl₄(NH₃)₂{μ-HN=C(O)Bu^t}₂]

2 citations , November 2022 in “Acta crystallographica. Section B, Structural science, crystal engineering and materials./Acta crystallographica. Section B, Structural science, crystal engineering and materials”

A new platinum complex was made and studied, which might help fight cancer better.

research Synthesis and Evaluation of 2‘-Substituted 4-(4‘-Carboxy- or 4‘-carboxymethylbenzylidene)-N-acylpiperidines: Highly Potent and in Vivo Active Steroid 5α-Reductase Type 2 Inhibitors

22 citations , June 2002 in “Journal of Medicinal Chemistry”

Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.

research Editor's evaluation: Plant Trans-Golgi Network/Early Endosome pH regulation requires Cation Chloride Cotransporter (CCC1)

September 2021

CCC1 is crucial for pH balance in plant cells, affecting growth and stress tolerance.

A Keratinocyte-Specific Epoxygenase, CYP2B12, Metabolizes Arachidonic Acid with Unusual Selectivity, Producing a Single Major Epoxyeicosatrienoic Acid

research A Keratinocyte-specific Epoxygenase, CYP2B12, Metabolizes Arachidonic Acid with Unusual Selectivity, Producing a Single Major Epoxyeicosatrienoic Acid

58 citations , April 1998 in “Journal of biological chemistry/The Journal of biological chemistry”

CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.

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