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Innovative Sequence of Docetaxel–Gemcitabine Based on Preclinical Data in the Treatment of Advanced Non-Small Cell Lung Cancer: A Phase I Study

research Innovative sequence of docetaxel–gemcitabine based on preclinical data in the treatment of advanced non small cell lung cancer: a phase I study

3 citations , February 2005 in “Lung Cancer”

The new chemotherapy combination for advanced lung cancer showed a 35.7% response rate but caused significant side effects.

research Interferon in the treatment of cutaneous T-cell lymphoma

107 citations , December 2003 in “Dermatologic Therapy”

Interferon, especially alfa interferon, is an effective treatment for cutaneous T-cell lymphoma with manageable side effects.

research Thiopurines: Recent Topics and Their Role in the Treatment of Inflammatory Bowel Diseases

21 citations , January 2021 in “Frontiers in Pharmacology”

Thiopurines help treat IBD but require genetic testing to avoid side effects.

research Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL

665 citations , April 2016 in “Nature communications”

Blocking specific proteins can help remove aging cells and might treat age-related diseases and promote hair growth.

research TICE salvage chemotherapy treats germ-cell tumors effectively

April 2007 in “Nature Clinical Practice Urology”

TICE salvage chemotherapy is effective for treating germ-cell tumors with poor prognosis.

The Effect of Active Hexose Correlated Compound in Modulating Cytosine Arabinoside-Induced Hair Loss, and 6-Mercaptopurine- and Methotrexate-Induced Liver Injury in Rodents

research The effect of active hexose correlated compound in modulating cytosine arabinoside-induced hair loss, and 6-mercaptopurine- and methotrexate-induced liver injury in rodents

14 citations , August 2009 in “Cancer epidemiology”

AHCC reduces hair loss and liver injury caused by chemotherapy in rodents.

research Gemcitabine combined with either pemetrexed or paclitaxel in the treatment of advanced non-small cell lung cancer

9 citations , April 2010 in “Lung cancer”

Combining gemcitabine with paclitaxel is more effective than with pemetrexed for advanced lung cancer.

research Adverse Systemic Reaction to Dinitrochlorobenzene

14 citations , June 1982 in “Archives of Dermatology”

A man had bad reactions to a hair loss treatment called DNCB.

research Unique Cutaneous Reaction to Second- and Third-Generation Tyrosine Kinase Inhibitors for Chronic Myeloid Leukemia

32 citations , September 2015 in “Dermatology”

Certain leukemia drugs can cause severe skin reactions that may require stopping treatment.

research Enzalutamide/finasteride/goserelin/zoledronic-acid

July 2024 in “Reactions Weekly”

research Supplementary Figures, Tables and Legends from Mobilizing Transit-Amplifying Cell-Derived Ectopic Progenitors Prevents Hair Loss from Chemotherapy or Radiation Therapy

March 2023

Boosting certain cell signals can prevent hair loss from chemotherapy and radiation.

research Preclinical Pharmacology, Antitumor Activity, and Development of Pharmacodynamic Markers for the Novel, Potent AKT Inhibitor CCT128930

65 citations , February 2011 in “Molecular cancer therapeutics”

CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.

research Intralesional therapy for the treatment of keratoacanthoma

25 citations , March 2019 in “Dermatologic therapy”

Intralesional therapy for keratoacanthoma is effective and has fewer side effects than systemic treatments.

research Curling of Hair in Two Female Patients Taking Alitretinoin

6 citations , October 2018 in “Drug safety - case reports”

Alitretinoin may cause irreversible hair curling as a side effect.

research A prospective study of daylight photodynamic therapy for treatment of actinic keratoses in an Irish population

April 2016 in “Journal of The American Academy of Dermatology”

Daylight photodynamic therapy is effective and well-tolerated for treating actinic keratoses with minimal side effects.

research Alopecia and Associated Toxic Agents: A Systematic Review

26 citations , January 2018 in “Skin appendage disorders”

Thallium, mercury, selenium, and colchicine strongly cause hair loss.

research Interferon alfa-2a in the treatment of cutaneous T cell lymphoma

209 citations , March 1989 in “Journal of The American Academy of Dermatology”

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

research Advances in the Management of Cutaneous Toxicities of Targeted Therapies

42 citations , April 2012 in “Seminars in Oncology”

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

$Synthesis and Structural Characterization of a New Dinuclear Platinum(III) Complex, [Pt2Cl4(NH3)2{μ-HN=C(O)Bu^t}2]$

research Synthesis and structural characterization of a new dinuclear platinum(III) complex, [Pt₂Cl₄(NH₃)₂{μ-HN=C(O)Bu^t}₂]

2 citations , November 2022 in “Acta crystallographica. Section B, Structural science, crystal engineering and materials./Acta crystallographica. Section B, Structural science, crystal engineering and materials”

A new platinum complex was made and studied, which might help fight cancer better.

research DERMATOLOGICAL ADVERSE EFFECTS OF CHEMOTHERAPEUTIC AGENTS: EXPERIENCE FROM A TERTIARY CENTRE

June 2017 in “Journal of evolution of medical and dental sciences”

About 22% of cancer patients had skin-related side effects from chemotherapy, but these were usually not severe enough to halt treatment.

research Chronic Toxicity Studies of the Potential Cancer Preventive 2-(Difluoromethyl)-dl-ornithine

January 1994 in “Toxicological Sciences”

Lower dosages of 2-(difluoromethyl)-dl-ornithine might reduce side effects, supporting further research.

research Non-Rash Skin Toxicities Associated with Novel Targeted Therapies

28 citations , December 2006 in “Clinical lung cancer”

Early recognition and management of skin side effects from new cancer therapies can prevent treatment delays.

Gemcitabine in Combination with Vinorelbine in Elderly Patients with Anthracycline- and Taxane-Pretreated Metastatic Breast Cancer

research Gemcitabine in combination with vinorelbine in elderly patients with anthracycline- and taxane-pretreated metastatic breast cancer

9 citations , February 2012 in “Cancer Chemotherapy and Pharmacology”

The combination of gemcitabine and vinorelbine is effective and safe for treating elderly patients with advanced breast cancer previously treated with anthracyclines and taxanes.

research Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/– mice

64 citations , March 2004 in “Journal of Clinical Investigation”

Targeting ornithine decarboxylase can help prevent skin cancer.

research Redox-Modulatory and MET-Inhibitory Triad: Synergistic Cytotoxicity of L-cysteine, NAC, and MET Inhibition in Cervical Cancer Cells

November 2025 in “Eurasian journal of applied biotechnology”

Combining L-cysteine, NAC, and a MET inhibitor significantly kills cervical cancer cells.

research A phase I study of MK-5108, an oral aurora A kinase inhibitor, in both monotherapy and in combination with docetaxel in patients with advanced solid tumors.

12 citations , May 2010 in “Journal of Clinical Oncology”

MK-5108 is safe and shows potential against tumors, especially alone.

Synthesis of Phenanthridin-3-One Derivatives: Non-Steroidal Inhibitors of Steroid 5-Alpha-Reductase

research Synthesis of phenanthridin-3-one derivatives: Non-steroidal inhibitors of steroid 5-α-reductase

20 citations , June 1995 in “Tetrahedron Letters”

New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.

research Single‐cell transcriptomics reveals a senescence‐associated IL ‐6/ CCR6 axis driving radiodermatitis

9 citations , July 2022 in “EMBO molecular medicine”

Blocking certain immune signals can reduce skin damage from radiation therapy.

research Rational Design and Synthesis of 4-((1R,2R)-2-Hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a Novel, Nonsteroidal Androgen Receptor Antagonist Devoid of Phototoxicity for Dermatological Indications

23 citations , October 2008 in “Journal of medicinal chemistry”

PF-998425 is a new, effective, and non-phototoxic treatment for skin conditions related to androgens.

research Alopecia in patients treated with molecularly targeted anticancer therapies

44 citations , September 2015 in “Annals of Oncology”

Targeted cancer therapies have a significant but lower risk of causing hair loss compared to chemotherapy.

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