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      WNT Signaling in Disease

      research WNT Signaling in Disease

      144 citations , August 2019 in “Cells”
      The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
      Liposomes in Dermatology Today

      research Liposomes in dermatology today

      140 citations , January 2009 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”
      Liposomes improve drug delivery and reduce skin irritation in dermatology.
      Exosomes for Repair, Regeneration, and Rejuvenation

      research Exosomes for repair, regeneration and rejuvenation

      135 citations , December 2015 in “Expert Opinion on Biological Therapy”
      Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.
      Androgenetic Alopecia and Microinflammation

      research Androgenetic alopecia and microinflammation

      131 citations , August 2000 in “International Journal of Dermatology”
      Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.
      Hair Loss in Women

      research Hair Loss in Women

      129 citations , October 2007 in “The New England Journal of Medicine”
      Over one-third of women experience hair loss, with female-pattern hair loss being most common, and treatments include minoxidil and possibly hair transplantation.
      Stem Cell Heterogeneity and Plasticity in Epithelia

      research Stem Cell Heterogeneity and Plasticity in Epithelia

      129 citations , May 2015 in “Cell Stem Cell”
      Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
      Obesity and the Skin

      research Obesity and the skin

      128 citations , September 2011 in “British Journal of Dermatology”
      Obesity is linked to various skin problems and may increase the risk of skin cancer.
      Regulatory T Cells: The Many Faces of Foxp3

      research Regulatory T Cells: the Many Faces of Foxp3

      125 citations , September 2019 in “Journal of Clinical Immunology”
      Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.
      Alopecia Areata: Pathogenesis And Treatment

      research Alopecia areata: Pathogenesis and treatment

      122 citations , November 1984 in “Journal of the American Academy of Dermatology”
      No single treatment is consistently effective for alopecia areata, and more research is needed.
      Extraskeletal Actions of Vitamin D

      research Extraskeletal actions of vitamin D

      119 citations , July 2016 in “Annals of the New York Academy of Sciences”
      Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.
      Potassium Channel Therapeutics at the Bedside

      research K channel therapeutics at the bedside

      119 citations , June 2005 in “Journal of Molecular and Cellular Cardiology”
      Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.
      Hair Regrowth

      research HAIR REGROWTH

      118 citations , April 1998 in “Dermatologic Clinics”
      Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.
      Smoking and the Skin: Effects and Therapeutic Potential

      research Smoking and the skin

      114 citations , February 2012 in “International Journal of Dermatology”
      Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.
      Cutaneous Toxicities of Cancer Therapy

      research Cutaneous toxicities of cancer therapy

      114 citations , March 2002 in “Current opinion in oncology/Current opinion in oncology, with cancerlit”
      Cancer therapy can cause various skin problems, including hair loss, skin darkening, painful hand-foot syndrome, and severe skin damage.
      Liposomes in Cosmeceuticals

      research Liposomes in cosmeceutics

      111 citations , March 2012 in “Expert Opinion on Drug Delivery”
      Liposomes could improve how skin care products work but are costly and not very stable.
      Sensitive Skin

      research Sensitive skin

      94 citations , January 2016 in “Journal of the European Academy of Dermatology and Venereology”
      Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.
      Alopecia Areata Update

      research Alopecia Areata Update

      85 citations , October 2012 in “Dermatologic Clinics”
      Alopecia Areata is an autoimmune condition often starting before age 20, with varied treatment success and a need for personalized treatment plans.