115 citations
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June 2004 in “Pediatrics” Children, especially teenagers, can get severe SARS-CoV infection with symptoms similar to adults, but they typically recover well with supportive care.
86 citations
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January 2019 in “Frontiers in Immunology” The document concludes that diagnosing and treating Human African Trypanosomiasis is challenging, but new treatments like fexinidazole are promising.
85 citations
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July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
77 citations
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June 2017 in “Advances in Therapy” New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.
76 citations
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April 2013 in “PLoS ONE” Chronic stress can cause hair loss by increasing oxidative stress, but antioxidants may help.
75 citations
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June 2019 in “International Journal of Molecular Sciences” Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.
67 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Chronic Telogen Effluvium may resolve after years and is diagnosed by examining the patient's history and clinical signs, with treatment aimed at underlying causes and possibly minoxidil.
67 citations
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March 1987 in “Journal of The American Academy of Dermatology” Minoxidil helps hair growth and prevents hair loss in androgenetic alopecia. It's safe and effective.
66 citations
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July 2007 in “Journal of Molecular Medicine” Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.
64 citations
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May 2019 in “Materials Science and Engineering: C” Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.
59 citations
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July 2015 in “Journal of Immunology” Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.
59 citations
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August 2010 in “Journal of The American Academy of Dermatology” Certain hairstyles and less hair oil use in African American girls can lead to scalp conditions like traction alopecia and seborrheic dermatitis.
52 citations
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June 1999 in “Endocrinology and Metabolism Clinics of North America” Antiandrogen treatments combined with oral contraceptives can help manage hair growth and hair loss in women with PCOS.
51 citations
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December 2011 in “The Journal of Dermatology” New treatments for severe hair loss often fail, but some patients see hair regrowth with specific therapies, and treatment should be tailored to the individual's situation.
47 citations
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September 2023 in “Pharmacological Reports” Vitamins A, B3, C, D, and E can improve skin health and immunity.
47 citations
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June 2014 in “Journal of Dermatological Treatment” Most treatments for lichen planopilaris were found to be generally unsatisfactory.
44 citations
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October 2017 in “British Journal of Dermatology” Botulinum toxin has potential for treating various skin conditions and improving wound healing.
42 citations
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April 2021 in “Journal of clinical pharmacology” Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.
39 citations
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January 2019 in “Journal of Dermatological Treatment” Ketoconazole cream is effective for skin conditions like seborrheic dermatitis and may help with hair loss and other skin issues, with generally mild side effects.
36 citations
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February 2017 in “BMC Complementary and Alternative Medicine” Geranium sibiricum extract helps hair grow and is more effective than minoxidil but can be toxic in high concentrations.
35 citations
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January 2019 in “Clinics in Dermatology” Syphilis has a wide range of symptoms that can look like other diseases, and if not treated, it can progress to a more serious stage, especially in HIV-positive patients.
34 citations
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April 2009 in “Expert Opinion on Pharmacotherapy” Some treatments work for common baldness, but there's less evidence for other hair loss types, and more research is needed.
33 citations
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October 2016 in “European Journal of Pharmaceutical Sciences” Effervescent formulations may improve minoxidil delivery, increasing effectiveness and reducing applications needed.
33 citations
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September 2016 in “Lasers in Surgery and Medicine” Fractional resurfacing is safe and effective for certain skin conditions in Asian patients, but care must be taken to avoid skin pigmentation issues.
33 citations
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December 2005 in “Archives of dermatology” Alefacept showed some effectiveness for alopecia areata but needs more research.
32 citations
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April 2016 in “Aaps Pharmscitech” Nanostructured lipid carriers improve minoxidil delivery for hair loss treatment.
31 citations
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April 2007 in “Experimental Dermatology” Stress in mice delays hair growth and treatments blocking substance P can partly reverse this effect.
29 citations
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March 1983 in “Journal of The American Academy of Dermatology” New treatments for psoriasis have improved effectiveness and may reduce long-term side effects when combined with standard therapies.
25 citations
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May 2009 in “International Journal of Dermatology” About one-third of dermatology patients in Ankara, Turkey use unconventional treatments for skin issues.
24 citations
,
September 2005 in “Journal of Cellular Biochemistry” Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.